Browsing by Title

Now showing items 87-106 of 227

    • Evaluation of anti-Bothrops asper venom activity of ethanolic extract of Brownea rosademonte leaves 

      SALAZAR, MARCOS; CHÉRIGO, LILIA; ACOSTA, HILDAURA; OTERO, RAFAEL; MARTÍNEZ-LUIS, SERGIO (2014-06-20)
      Significant inhibition of the coagulant and hemorrhagic effects of Bothrops asper venom was demonstrated by ethanolic extract prepared from the leaves of Brownea rosademonte. In vitro experiments preincubating 5.5 mg of ...

    • Evaluation of antiparasitic, anticancer, antimicrobial and hypoglycemic properties of organic extracts from Panamanian mangrove plants 

      Lopez, Dioxelis; Cherigo, Lilia; de Sedas, Alejandro; Spadafora, Carmenza; Martinez, Luis sergio (2018-01-02)
      To investigate 33 organic extracts of mangrove plants for: antiparasitic, anticancer, and antibacterial activities, as well as their ability to inhibit the activity of the 毩-glucosidase enzyme. Methods: Leaves from all ...

    • Evaluation of antiparasitic, anticancer, antimicrobial and hypoglycemic properties of organic extracts from Panamanian mangrove plants 

      Lopez, Dioxelis; Cherigo, Lilia; de Sedas, Alejandro; Spadafora, Carmenza; Martinez, Luis sergio (2018-01-02)
      To investigate 33 organic extracts of mangrove plants for: antiparasitic, anticancer, and antibacterial activities, as well as their ability to inhibit the activity of the 毩-glucosidase enzyme. Methods: Leaves from all ...

    • Evaluation of phytotoxic, cytotoxic and antiparasitic in vitro activities of Borreria verticillata, a weed of Panamanian coffee crops. 

      Cherigo, L.; Lezcano, J.; Spadafora, Carmenza; Martínez-Luis, Sergio (2012-01-01)
      In recent years, there have been significant changes in weed populations in different agricultural production systems. Coffee production is economically important in the Republic of Panama, and the specie Borreria verticillata ...

    • Evidence for Pleistocene Population Divergence and Expansion of Anopheles albimanus in Southern Central America 

      Loaiza, Jose R.; Scott, Marilyn E.; Bermingham, Eldredge; Rovira, Jose; Conn, Jan E. (2010-01-05)
      The micro-geographic structure of Anopheles albimanus was studied in southern Central America using partial sequences of the mtDNA cytochrome oxidase subunit I gene (COI). Analysis of molecular variance supported significant ...

    • Exposure to the leaf litter microbiome of healthy adults protects seedlings from pathogen damage 

      Christian, Natalie; Herre, Edward Allen; Mejia, Luis C.; Clay, Keith (2017-07-05)
      It is increasingly recognized that microbiota affect host health and physiology. However, it is unclear what factors shape microbiome community assembly in nature, and how microbiome assembly can be manipulated to improve ...

    • Extracellular vesicles carrying lactate dehydrogenase induce suicide in increased population density of Plasmodium falciparum in vitro 

      Correa, Ricardo; Coronado, Lorena M.; Caballero, Zuleima; Faral, Paula; Robello, Carlos; Spadafora, Carmenza (2019-03-25)
      Even with access to sufficient nutrients and atmosphere, Plasmodium falciparum can barely be cultured at maximum growth capacity in vitro conditions. Because of this behavior, it has been suggested that P. falciparum has ...

    • Extracellular Vesicles Could Carry an Evolutionary Footprint in Interkingdom Communication 

      Correa, Ricardo; Caballero, Zuleima; Luis Fernando, De León; Spadafora, Carmenza (Frontiers, 2020-03-03)
      Extracellular vesicles (EVs) are minute particles secreted by the cells of living organisms. Although the functional role of EVs is not yet clear, recent work has highlighted their role in intercellular communication. Here, ...

    • Factores asociados al no uso de métodos anticonceptivos durante el puerperio, hospital Víctor Ramos Guardia-Huaraz, 2017 

      Mejia, Carlos; Maiza, Lorena; Diaz, Pineda; Rosario, Marleny (2018-01-01)
      Se planteó el siguiente problema: Cuáles son los factores asociados al no uso de métodos anticonceptivos durante el puerperio, Hospital Víctor Ramos Guardia - Huaraz, 2017 Con el objetivo general de determinar los factores ...

    • First report of Tomato leaf curl Sinaloa virus infecting tomato crops in Panama 

      Herrera-Vásquez, J.A.; Ortega, D.; Romero, A.B.; Davino, S.; Mejía, L.C.; Panno, S.; Davino, M. (2015-06-21)
      In April 2011 and September 2012, virus-like symptoms were observed in open field- and greenhouse-grown tomato crops (Solanum lycopersicum) in Chiriquí, the westernmost province of Panama. Samples from symptombearing plants ...

    • First Whole Genome Sequence of Anaplasma platys, an Obligate Intracellula Rickettsial Pathogen of Dogs 

      Llanes, Alejandro; Rajeev, Sreekumari (2020-04-10)
      We have assembled the first genome draft of Anaplasma platys, an obligate intracellular rickettsia, and the only known bacterial pathogen infecting canine platelets. A. platys is a not-yet-cultivated bacterium that causes ...

    • Forest disturbance and vector transmitted diseases in thelowland tropical rainforest of central Panama 

      Loaiza, Jose R.; Rovira, Jose R.; Sanjur, Oris I.; Altagracia Zepeda, Jesus; Pecor, James E.; Foley, Desmond H.; Dutari, Larissa; Radtke, Meghan; Pongsiri, Montira J.; Smith Molinar, Octavio; Laporta, Gabriel Z. (2019-07-07)
      objective To explore possible changes in the community attributes of haematophagous insects as afunction of forest disturbance. We compare the patterns of diversity and abundance, plus thebehavioural responses of three ...

    • Frequency of Toxoplasma gondii and Risk Factors Associated with the Infection in Stray Dogs and Cats of Panama 

      Fábrega, Lorena; Restrepo, Carlos M.; Torres, Alicia; Smith, Diorene; Chan, Patricia; Pérez, Dimas; Cumbrera, Alberto; Caballero E., Zuleima (2020-06-19)
      Stray animals such as dogs and cats have an important role in maintaining the transmission cycles and dissemination of Toxoplasma gondii. Therefore, the objective of this study was to evaluate the frequency of T. gondii ...

    • Fungal endophytes limit pathogen damage in a tropical tree 

      Arnold, A. Elizabeth; Mejía, Luis Carlos; Kyllo, Damond; Rojas, Enith I.; Maynard, Zuleyka; Robbins, Nancy; Herre, Edward Allen (2003-10-23)
      Every plant species examined to date harbors endophytic fungi within its asymptomatic aerial tissues, such that endophytes represent a ubiquitous, yet cryptic, component of terrestrial plant communities. Fungal endophytes ...

    • The genome of Leishmania panamensis: insights into genomics of the L. (Viannia) subgenus. 

      Llanes, Alejandro; Restrepo, Carlos Mario; Del Vecchio, Gina; Anguizola, Franklin Jose´; Lleonart, Ricardo (2015-02-24)
      Kinetoplastid parasites of the Leishmania genus cause several forms of leishmaniasis. Leishmania species pathogenic to human are separated into two subgenera, Leishmania (Leishmania) and L. (Viannia). Species from the ...

    • Genome Sequences of Chikungunya Virus Isolates from Bolivia 

      B. França, Caio M.; Loayza, Roxana; Roca, Yelin; Montaño Arias, Ana Maria; Tinajeros, Freddy; Loaiza, Jose R.; Takyar, Anshule; Gilman, Robert H.; Milleri, Matthew J. (2020-04-16)
      We generated nine coding-complete chikungunya virus genome sequences from blood samples collected during the early 2015 outbreak in Bolivia. Relative to other publicly available chikungunya sequences, the Bolivian samples ...

    • Genome-wide discovery and development of polymorphic microsatellites from Leishmania panamensis parasites circulating in central Panama 

      Restrepo, Carlos M.; Llanes, Alejandro; De La Guardia, Carolina; Lleonart, Ricardo (2015-10-12)
      The parasite Leishmania panamensis is the main cause of leishmaniasis in Panama. The disease is largely uncontrolled, with a rising incidence and no appropriate control measures. While microsatellites are considered some ...

    • Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo 

      Llanes, Alejandro; Restrepo, Carlos Mario; Ferreiro, Pablo Riesgo; Rajeev, Sreekumari (2018-05-22)
      Leptospira borgpetersenii serovar Hardjo colonizes cattle kidneys and may occasionally infect humans and other mammals. Strains belonging to two clonal subtypes (types A and B) with marked differences in their pathogenicity ...

    • Geographic Expansion of the Invasive Mosquito Aedes albopictus across Panama— Implications for Control of Dengue and Chikungunya Viruses 

      Miller, Matthew J.; Loaiza, Jose R. (2015-01-08)
      The Asian tiger mosquito, Aedes (Stegomyia) albopictus, is an invasive species that has expanded its territory to over 40% of the earth’s terrestrial landmass in the last 30 years [1]. Ae. albopictus is an efficient vector ...

    • The global burden of tuberculosis: results from the Global Burden of Disease Study 2015 

      Kyu, Hmwe H; Maddison, Emilie R; Henry, Nathaniel J; Mumford, John Everett; Barber, Ryan; Shields, Chloe; Brown, Jonathan C; Nguyen, Grant; Carter, Austin; Wolock, Timothy M; Wang, Haidong; Liu, Patrick Y; Reitsma, Marissa; Ross, Jennifer M; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbas, Kaja; Abera, Mubarek; Abera, Semaw Ferede; Hareri, Habtamu Abera; Ahmed, Muktar; Alene, Kefyalew Addis; Alvis-Guzman, Nelson; Amo-Adjei, Joshua; Andrews, Jason; Ansari, Hossein; Antonio, Carl Abelardo; Anwari, Palwasha; Asayesh, Hamid; Atey, Tesfay Mehari; Atre, Sachin; Barac, Aleksandra; Beardsley, Justin; Bedi, Neeraj; Bensenor, Isabela; Beyene, Addisu Shunu; Butt, Zahid Ahmad; Cardona, Pere-Joan; Christopher, Devasahayam; Dandona, Lalit; Dandona, Rakhi; Deribe, Kebede; Deribew, Amare; Ehrenkranz, Rebecca; El Sayed Zaki, Maysaa; Endries, Aman; Feyissa, Tesfaye R; Fischer, Florian; Gai, Ruoyan; Garcia-Basteiro, Alberto L; Gebrehiwot, Tsegaye Tewelde; Gesesew, Hailay; Getahun, Belete; Gona, Philimon; Goodridge, Amador; Gugnani, Harish; Haghparast-Bidgoli, Hassan; Bugssa Hailu, Gessessew; Hassen, Hamid Yimam; Hilawe, Esayas; Horita, Nobuyuki; Jacobsen, Kathryn H; Jonas, Jost B; Kasaeian, Amir; Kedir, Muktar Sano; Kemmer, Laura; Khader, Yousef; Khan, Ejaz; Khang, Young-Ho; Khoja, Abdullah T; Kim, Yun Jin; Koul, Parvaiz; Koyanagi, Ai; Krohn, Kristopher J; Kumar, G Anil; Kutz, Michael; Lodha, Rakesh; Magdy, Hassan; Razek, El; Majdzadeh, Reza; Manyazewal, Tsegahun; Memish, Ziad; Mendoza, Walter; Mezgebe, Haftay Berhane; Mohammed, Shafiu; Ogbo, Felix Akpojene; Oh, In-Hwan; Oren, Eyal; Osgood-Zimmerman, Aaron; Pereira, David; Plass, Dietrich; Pourmalek, Farshad; Qorbani, Mostafa; Rafay, Anwar; Rahman, Mahfuzar; Rai, Rajesh Kumar; Rao, Puja C; Ray, Sarah E; Reiner, Robert; Reinig, Nickolas; Safiri, Saeid; Salomon, Joshua A; Sandar, Logan; Sartorius, Benn; Shamsizadeh, Morteza; Shey, Muki; Shifti, Desalegn Markos; Shore, Hirbo; Singh, Jasvinder; Sreeramareddy, Chandrashekhar T; Swaminathan, Soumya; Swartz, Scott J; Tadese, Fentaw; Tedla, Bemnet Amare; Tegegne, Balewgizie Sileshi; Tessema, Belay; Topor-Madry, Roman; Nnanna Ukwaja, Kingsley; Uthman, Olalekan A; Vlassov, Vasiliy; Vollset, Stein Emil; Wakayo, Tolassa; Weldegebreal, Solomon; Westerman, Ronny; Workicho, Abdulhalik; Yonemoto, Naohiro; Yoon, Seok-Jun; Yotebieng, Marcel; Naghavi, Mohsen; Hay, Simon I; Vos, Theo; Murray, Christopher JL (2018-03-01)
      Background The UN’s Sustainable Development Goals (SDGs) are grounded in the global ambition of “leaving no one behind”. Understanding today’s gains and gaps for the health-related SDGs is essential for decision makers as ...