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Anti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oil
| dc.contributor.author | Durant, Armando A | |
| dc.contributor.author | Rodríguez, Candelario | |
| dc.contributor.author | Herrera, Liuris | |
| dc.contributor.author | Almanza, Alejandro | |
| dc.contributor.author | Santana, Ana I | |
| dc.contributor.author | Spadadora, Carmenza | |
| dc.contributor.author | Gupta, Mahabir P | |
| dc.date.accessioned | 2020-06-20T05:14:28Z | |
| dc.date.available | 2020-06-20T05:14:28Z | |
| dc.date.issued | 2014-01-13 | |
| dc.identifier.other | http://www.malariajournal.com/content/13/1/18 | |
| dc.identifier.uri | http://repositorio-indicasat.org.pa/handle/123456789/102 | |
| dc.description | Plinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil of this plant has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS of this essential oil have not been reported before. Anti-malarial activity of the essential oil (EO) was evaluated in vitro against chloroquine-sensitive HB3 and chloroquine-resistant W2 strains of Plasmodium falciparum. Synergistic effect of chloroquine and the EO on parasite growth was evaluated by calculating the combination index. A methodology involving headspace solid phase microextraction and gas chromatography-m | en_US |
| dc.description.abstract | Plinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil of this plant has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS of this essential oil have not been reported before. Anti-malarial activity of the essential oil (EO) was evaluated in vitro against chloroquine-sensitive HB3 and chloroquine-resistant W2 strains of Plasmodium falciparum. Synergistic effect of chloroquine and the EO on parasite growth was evaluated by calculating the combination index. A methodology involving headspace solid phase microextraction and gas chromatography-m | en_US |
| dc.format | application/pdf | |
| dc.language.iso | eng | en_US |
| dc.rights | Info:eu-repo/semantics/openAccess | |
| dc.rights | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Malaria | en_US |
| dc.subject | Plinia cerrocampanensis | en_US |
| dc.subject | Plasmodium falciparum | en_US |
| dc.subject | Essential oil | en_US |
| dc.subject | Anti-malarial activity | en_US |
| dc.subject | Solid phase microextraction | en_US |
| dc.subject | Gas chromatography-mass spectrometry | en_US |
| dc.title | Anti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oil | en_US |
| dc.type | info:eu-repo/semantics/article | en_US |
| dc.type | Info:eu-repo/semantics/publishedversion |
