Browsing Investigación by Title
Now showing items 58-77 of 227
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Development of Aluminium Based Surface Nano Composites Using Friction Stir Processing
(2018-02-22)Friction Stir Processing is a relatively new technique which has been developed for microstructural modification of metallic materials through intense, localized plastic deformation. The current research work deals with ... -
Development of anthracycline-induced dilated cardiomyopathy due to mutation on LMNA gene in a breast cancer patient: a case report
(2019-07-16)Background Anthracyclines are highly effective anticancer medication prescribed for the treatment of breast cancer. Nevertheless, the use of anthracyclines as chemotherapeutic agents involves a risk for development of ... -
Development of anthracycline-induced dilated cardiomyopathy due to mutation on LMNA gene in a breast cancer patient: a case report
(2019-07-16)Background Anthracyclines are highly effective anticancer medication prescribed for the treatment of breast cancer. Nevertheless, the use of anthracyclines as chemotherapeutic agents involves a risk for development of ... -
Development of Monoclonal Antibodies Against Cry1Ac/Ab Protein for Designing of Sandwich ELISA to Detect BT Toxin from Cotton Seeds and Leaves
(2019-12-30)The design of the study is to develop monoclonal antibodies against Cry1Ac/Ab protein for designing os sandwich ELISA(hybridoma technology). Hybridoma technology was invented by Cesar Milstein and Georges J.F Kohler in the ... -
Differential responses of osteoblast lineage cells to nanotopographically-modified, microroughened titaniumealuminumevanadium alloy surfaces
(2012-09-16)Surface structural modifications at the micrometer and nanometer scales have driven improved success rates of dental and orthopaedic implants by mimicking the hierarchical structure of bone. However, how initial ... -
Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species
(2017-08-07)A recent untargeted metabolomics investigation into the chemical profile of 10 organic extracts from cf. Symploca spp. revealed several interesting chemical leads for further natural product drug discovery. Subsequent ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
(2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
(2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ... -
Disturbance and mosquito diversity in the lowland tropical rainforest of central Panama
(2017-08-03)The Intermediate Disturbance Hypothesis (IDH) is well-known in ecology providing an explanation for the role of disturbance in the coexistence of climax and colonist species. Here, we used the IDH as a framework to describe ... -
Diverse novel phleboviruses in sandflies from the Panama Canal area, Central Panama
(2019-05-03)The genus Phlebovirus (order Bunyavirales, family Phenuiviridae) comprises 57 viruses that are grouped into nine speciescomplexes. Sandfly-transmitted phleboviruses are found in Europe, Africa and the Americas and are ... -
Diversity and Allelopathic Potential of Weeds among Panamanian Coffee Crops
(2018-08-22)Worldwide, coffee is one of the most highly consumed and produced crops. Coffee production is a significant activity in the Panamanian economy, mainly in rural communities and among indigenous groups in the Chiriquí ... -
DNA Repair Mechanisms as Drug Targets in Prokaryotes
(2011-07-01)Nowadays, a great amount of pathogenic bacteria has been identified such as Mycobacterium sp. and Helicobacter pylori and have become a serious health problem around the world. These bacteria have developed several DNA ... -
Dudawalamides A−D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens
(2017-05-23)HPLC. DudA family of 2,2-dimethyl-3-hydroxy-7-octynoic acid (Dhoya)-containing cyclic depsipeptides, named dudawalamides A−D (1−4), was isolated from a Papua New Guinean field collection of the cyanobacterium Moorea producens ... -
Dynamics and diversity of bacteria associated with the disease vectors Aedes aegypti and Aedes albopictus
(2019-08-21)Aedes aegypti and Aedes albopictus develop in the same aquatic sites where they encounter microorganisms that infuence their life history and capacity to transmit human arboviruses. Some bacteria such as Wolbachia are ... -
ECOLOGICAL IMPLICATIONS OF ANTI-PATHOGEN EFFECTS OF TROPICAL FUNGAL ENDOPHYTES AND MYCORRHIZAE
(2007-03-01)We discuss studies of foliar endophytic fungi (FEE) and arbuscular mycorrhizal fungi (AMF) associated with Theobroma cacao in Panama. Direct, experimentally controlled comparisons of endophyte free (E—) and endophyte ... -
Effect of Post Weld Heat Treatments on the Elevated Temperature Mechanical Properties of Ti6Al4V Friction Welds
(2018-02-09)The {\alpha}+\b {eta} titanium alloy (Ti6Al4V) has been successfully joined using rotary friction welding. To investigate the influence of post weld heat treatments on the microstructure and mechanical properties of the ... -
The effects of combined micron-/submicron-scale surface roughness and nanoscale features on cell proliferation and differentiation
(2011-02-08)Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants. Previous studies have shown that surface roughness at the micro- and submicro-scales promotes osseointegration by enhancing ... -
The effects of impaired cerebral circulation on Alzheimer's disease pathology: evidence from animal studies.
(2014-01-01)Persistent systemic hypoxia, a direct consequence of alterations in vascular function, can compromise the brain by increasing the risk of developing dementias such as Alzheimer’s disease (AD). Vascular contributions to ... -
Effects of structural properties of electrospun TiO2 nanofiber meshes on their osteogenic potential
(2011-10-31)Ideal outcomes in the field of tissue engineering and regenerative medicine involve biomaterials that can enhance cell differentiation and production of local factors for natural tissue regeneration without the use of ... -
Electrical Polarization of Titanium Surfacesfor the Enhancement of Osteoblast Differentiation
(2013-08-29)Electrical stimulation has been used clinically to promote bone regeneration in cases of fractures with delayed union or nonunion, with several in vitro and in vivo reports suggesting its beneficial effects on bone formation. ...