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In vitro evidence that an aqueous extract of Centella asiatica modulates α-synuclein aggregation dynamics.
(2014-01-01)
α-Synuclein aggregation is one of the major etiological factors implicated in Parkinson's disease (PD). The prevention of ggregation of α-synuclein is a potential therapeutic intervention for preventing PD. The discovery ...
α-Synuclein misfolding versus aggregation relevance to Parkinson’s disease: Critical assessment and modeling
(2015-06-01)
α-Synuclein, an abundant and conserved presynaptic brain protein, is implicated as a critical factor in
Parkinson’s disease (PD). The aggregation of α-synuclein isbelieved to be a critical event in the isease process. ...