Browsing Artículos Científicos by Author "Rao, KS Jagannatha"
Now showing items 21-25 of 25
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A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
Madrigal, Marialaura; Rao, KS Jagannatha; Riordan, Neil H (2014-10-11)The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ... -
Revisiting metal toxicity in neurodegenerative diseases and stroke: Therapeutic potential.
Mitra, Joy; Vasquez, Velmarini; Hegde, Pavana M.; Boldogh, Istvan; Mitra, Sankar; Kent, Thomas A.; Rao, KS Jagannatha; Hegde, Muralidhar L (2015-01-23)Excessive accumulation of pro-oxidant metals, observed in affected brain regions, has consistently been implicated as a ontributor to the brain pathology including neurodegenerative diseases and acute injuries such as ... -
TDP-43/FUS in motor neuron disease: complexity and challenges
Guerrero, Erika N; Wang, Haibo; Mitra, Joy; Hegde, Pavana M; Stowell, Sara E; Liachko, Nicole F; Kraemer, Brian C; Garruto, Ralph M; Rao, KS Jagannatha; Hegde, Muralidhar L (2016-10-01)Amyotrophic lateral sclerosis (ALS), a common motor neuron disease affecting two per 100,000 people worldwide, encompasses at least five distinct pathological subtypes, including, ALS-SOD1, ALS-C9orf72, ALS-TDP-43, ALS-FUS ... -
Vacuolar Targeting of Cry1Ac and its Effects on Expression and Stability in Tobacco.
Singh, Vivek Kumar; Gothandapani, Sellamuthu; Phanindra, Mullapudi Lakshmi Venkata; Nain, Vikrant; Sreevathsa, Rohini; Rao, KS Jagannatha; Kumar, Polumetla Ananda (2014-07-01)Increasing heterologous expression of delta endotoxins of Bacillus thuringiensis in transgenic plants is being actively pursued as a means to increase their efficacy and to delay insect resistance. To examine if vacuoles ... -
α-Synuclein misfolding versus aggregation relevance to Parkinson’s disease: Critical assessment and modeling
Berrocal, Ruben; Vasquez, Velmarini; Rao Krs, Sambasiva; Gadad, Bharathi S; Rao, KS Jagannatha (2015-06-01)α-Synuclein, an abundant and conserved presynaptic brain protein, is implicated as a critical factor in Parkinson’s disease (PD). The aggregation of α-synuclein isbelieved to be a critical event in the isease process. ...