Browsing Artículos Científicos by Author "Gerwick, Lena"

Now showing items 1-2 of 2

    • Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group 

      Shao, Chang-Lun; Feng Mou, Xiao; Cao, Fei; Spadafora, Carmenza; Glukhov, Evgenia; Gerwick, Lena; Yun Wang, Chang; Gerwick, William H. (2018-01-12)
      We reported previously the discovery of the potent antimalarial 40-membered macrolide bastimolide A (1) from the tropical marine cyanobacterium Okeania hirsute. Continued investigation has led to the discovery of a new ...

    • Coibacins A D, Antileishmanial Marine Cyanobacterial Polyketides with Intriguing Biosynthetic Origins 

      Balunas, Marcy J.; Grosso, Manuel F.; Villa, Francisco A.; Engene, Niclas; McPhail, Kerry L.; Tidgewell, Kevin; Pineda, Laura M.; Gerwick, Lena; Spadafora, Carmenza; Kyle, Dennis E.; Gerwick, William H. (2012-08-03)
      Four unsaturated polyketide lactone derivatives, coibacins A-D, were isolated from a Panamanian marine cyanobacterium, cf. Oscillatoria sp. The two different types of termini observed in these co-occurring metabolites, ...