Browsing Artículos Científicos by Author "Hegde, Muralidhar L."
Now showing items 1-2 of 2
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An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson’s Disease
Vasquez, Velmarini; Mitra, Joy; Perry, George; Rao, KS Jagannatha; Hegde, Muralidhar L. (2018-11-08)Altered expression of α-synuclein is linked to Parkinson’s disease (PD). A major challenge to explore how the increased α-synuclein affect neurotoxicity is the lack of a suitable human neuronal cell model that mimics this ... -
New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases
Mitra, Joy; Guerrero, Erika N.; Hegde, Pavana M.; Wang, Haibo; Boldogh, Istvan; Sharaf Rao, Kosagi; Mitra, Sankar; Hegde, Muralidhar L. (biomolecules, 2014-07-17)The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, e.g., oxidative ...