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Comparative study on anti-oxidant and anti-inflammatory activities of Caesalpinia crista and Centella asiatica leaf extracts
(2014-04-01)
Background:
Amyloidosis, oxidative stress and inflammation have been strongly implicated in neurodegenerative disorders like Alzheimer's disease. Traditionally, Caesalpinia crista and Centella asiatica leaf extracts are ...
In vitro evidence that an aqueous extract of Centella asiatica modulates α-synuclein aggregation dynamics.
(2014-01-01)
α-Synuclein aggregation is one of the major etiological factors implicated in Parkinson's disease (PD). The prevention of ggregation of α-synuclein is a potential therapeutic intervention for preventing PD. The discovery ...
The effects of impaired cerebral circulation on Alzheimer's disease pathology: evidence from animal studies.
(2014-01-01)
Persistent systemic hypoxia, a direct consequence of alterations in vascular function, can compromise the brain by
increasing the risk of developing dementias such as Alzheimer’s disease (AD). Vascular contributions to ...
Vacuolar Targeting of Cry1Ac and its Effects on Expression and Stability in Tobacco.
(2014-07-01)
Increasing heterologous expression of delta endotoxins of Bacillus thuringiensis in transgenic plants is being actively pursued as a
means to increase their efficacy and to delay insect resistance. To examine if vacuoles ...
A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
(2014-10-11)
The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ...
The lipid content and fatty acid composition of four eastern central Pacific native fish species
(2014-02-01)
Fish is an important source of nutritious n-3 fatty acids, which are necessary for the prevention of cardiovascular and neurological diseases. The lipid content and fatty acid composition of economically important fishes ...
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
(2014-07-17)
The primary cause (s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, eg, oxidative ...