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dc.contributor.authorDurant, Armando A
dc.contributor.authorRodríguez, Candelario
dc.contributor.authorHerrera, Liuris
dc.contributor.authorAlmanza, Alejandro
dc.contributor.authorSantana, Ana I
dc.contributor.authorSpadadora, Carmenza
dc.contributor.authorGupta, Mahabir P
dc.date.accessioned2020-06-20T05:14:28Z
dc.date.available2020-06-20T05:14:28Z
dc.date.issued2014-01-13
dc.identifier.otherhttp://www.malariajournal.com/content/13/1/18
dc.identifier.urihttp://repositorio-indicasat.org.pa/handle/123456789/102
dc.descriptionPlinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil of this plant has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS of this essential oil have not been reported before. Anti-malarial activity of the essential oil (EO) was evaluated in vitro against chloroquine-sensitive HB3 and chloroquine-resistant W2 strains of Plasmodium falciparum. Synergistic effect of chloroquine and the EO on parasite growth was evaluated by calculating the combination index. A methodology involving headspace solid phase microextraction and gas chromatography-men_US
dc.description.abstractPlinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil of this plant has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS of this essential oil have not been reported before. Anti-malarial activity of the essential oil (EO) was evaluated in vitro against chloroquine-sensitive HB3 and chloroquine-resistant W2 strains of Plasmodium falciparum. Synergistic effect of chloroquine and the EO on parasite growth was evaluated by calculating the combination index. A methodology involving headspace solid phase microextraction and gas chromatography-men_US
dc.formatapplication/pdf
dc.language.isoengen_US
dc.rightsInfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectMalariaen_US
dc.subjectPlinia cerrocampanensisen_US
dc.subjectPlasmodium falciparumen_US
dc.subjectEssential oilen_US
dc.subjectAnti-malarial activityen_US
dc.subjectSolid phase microextractionen_US
dc.subjectGas chromatography-mass spectrometryen_US
dc.titleAnti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oilen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeInfo:eu-repo/semantics/publishedversion


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