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Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells
(2018-02-08)
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The cellular immune response to mycobacteria has been characterized extensively, but the antibody response remains underexplored. The present study ...
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
(American Journal of Respiratory and Critical Care Medicine, 2018-09-15)
Tuberculosis (TB) remains the leading cause of death from a single infectious agent, followed by HIV/AIDS (1). Emerging countries, such as Panama, have not been able to curb TB infection rates. The development of novel ...
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
(2018-06-13)
Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...