Investigación: Recent submissions
Now showing items 101-120 of 227
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Dynamics and diversity of bacteria associated with the disease vectors Aedes aegypti and Aedes albopictus
(2019-08-21)Aedes aegypti and Aedes albopictus develop in the same aquatic sites where they encounter microorganisms that infuence their life history and capacity to transmit human arboviruses. Some bacteria such as Wolbachia are ... -
Habitat disturbance and the organization of bacterial communities in Neotropical hematophagous arthropods
(2019-09-06)The microbiome plays a key role in the biology, ecology and evolution of arthropod vectors of human pathogens. Vector-bacterial interactions could alter disease transmission dynamics through modulating pathogen replication ... -
Mycobacterium tuberculosis Isolates from Single Outpatient Clinic in Panama City Exhibit Wide Genetic Diversity
(2014-08-06)Understanding Mycobacterium tuberculosis biodiversity and transmission is significant for tuberculosis control. This short report aimed to determine the genetic diversity of M. tuberculosis isolates from an outpatient ... -
Storage in ultra-low-temperature decreases the levels of IgM anticardiolipin antibody in serum samples from tuberculosis patients
(2014-06-01)The evaluation of novel tuberculosis (TB) biomarkers relies on analysis of previously stored sample sets. We aimed to determine the effect of storage temperature on serum IgM anticardiolipin antibody levels in samples from ... -
Tuberculosis remains a challenge despite economic growth in Panama
(2014-03-01)Tuberculosis (TB) is a disease associated with inequality, and wise investment of economic resources is considered critical to its control. Panama has recently secured its status as an upper-middle-income country with ... -
Detecting space-time clusters of dengue fever in Panama after adjusting for vector surveillance data
(2019-09-23)Long term surveillance of vectors and arboviruses is an integral aspect of disease prevention and control systems in countries affected by increasing risk. Yet, little effort has been made to adjust space-time risk estimation ... -
COVID-19 pandemic in Panama: lessons of the unique risks and research opportunities for Latin America
(2020-06)The Republic of Panama has the second most unequally distributed wealth in Central America, has recently entered the list of countries affected by the COVID-19 pandemic, and has one of the largest testing rate per inhabitant ... -
Application of matrix-assisted laser desorption/ionization mass spectrometry to identify species of Neotropical Anopheles vectors of malaria
(2019-03-22)Background: Malaria control in Panama is problematic due to the high diversity of morphologically similar Anopheles mosquito species, which makes identifcation of vectors of human Plasmodium challenging. Strategies by ... -
High clustering rates of multidrug-resistant Mycobacterium tuberculosisgenotypes in Panama
(2013-12-01)Background: Tuberculosis continues to be one of the leading causes of death worldwide and in the American region. Although multidrug-resistant tuberculosis (MDR-TB) remains a threat to TB control in Panama, few studies ... -
Serum samples can be substituted by plasma samples for the diagnosis of paratuberculosis
(2013-01-01)Employing plasma samples rather than serum samples for serological paratuberculosis diagnosis is practical, especially when bovine TB is assessed in the same cattle herd with the gamma interferon bovine avian (IFN- BA) ... -
Anti-lipid antibody in M. tuberculosis infection--basis for a new biomarker-based test to monitor treatment response
(2011-01-01)Tuberculosis (TB) faces difficult challenges for its treatment and control. Both the diagnosis of TB and Mycobacterium tuberculosis (M. tuberculosis) drug susceptibility testing take weeks and clinicians often do not know ... -
High infestation of invasive Aedes mosquitoes in used tires along the local transport network of Panama
(2019-05-27)Background: The long‑distance dispersal of the invasive disease vectors Aedes aegypti and Aedes albopictus has intro‑ duced arthropod‑borne viruses into new geographical regions, causing a significant medical and economic ... -
tempo and mode of allopatric divergence in the weakly electric fish Sternopygus dariensis in the Isthmus of Panama
(2019-12-11)Spatial isolation is one of the main drivers of allopatric speciation, but the extent to which spatiallysegregated populations accumulate genetic differences relevant to speciation is not always clear. We used data from ... -
Agua Salud alphavirus defines a novel lineage of insect- specific alphaviruses discovered in the New World
(2020-01-01)The genus Alphavirus harbours mostly insect- transmitted viruses that cause severe disease in humans, livestock and wildlife. Thus far, only three alphaviruses with a host range restricted to insects have been found in ... -
α-Synuclein misfolding versus aggregation relevance to Parkinson’s disease: Critical assessment and modeling
(2015-06-01)α-Synuclein, an abundant and conserved presynaptic brain protein, is implicated as a critical factor in Parkinson’s disease (PD). The aggregation of α-synuclein isbelieved to be a critical event in the isease process. ... -
The lipid content and fatty acid composition of four eastern central Pacific native fish species
(2014-02-01)Fish is an important source of nutritious n-3 fatty acids, which are necessary for the prevention of cardiovascular and neurological diseases. The lipid content and fatty acid composition of economically important fishes ... -
Production of pullulan using jaggery as substrate by Aureobasidium pullulans MTCC 2195
(2016-04-01)Shake-flask fermentation, under batch cultivation, was investigated for the production of fungal exopolysaccharide, pullulan using jaggery (a traditional concentrated sugar cane juice) as a carbon substrate by Aureobasidium ... -
TDP-43/FUS in motor neuron disease: complexity and challenges
(2016-10-01)Amyotrophic lateral sclerosis (ALS), a common motor neuron disease affecting two per 100,000 people worldwide, encompasses at least five distinct pathological subtypes, including, ALS-SOD1, ALS-C9orf72, ALS-TDP-43, ALS-FUS ... -
Development of anthracycline-induced dilated cardiomyopathy due to mutation on LMNA gene in a breast cancer patient: a case report
(2019-07-16)Background Anthracyclines are highly effective anticancer medication prescribed for the treatment of breast cancer. Nevertheless, the use of anthracyclines as chemotherapeutic agents involves a risk for development of ... -
Proteomic fingerprint identification of Neotropical hard tick species (Acari: Ixodidae) using a self-curated mass spectra reference library
(2020-04-14)Matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry is an analytical method that detects macromolecules that can be used as biomarkers for taxonomic identification in arthropods. The ...