Now showing items 1-3 of 3

    • Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells 

      Ordoñez, Ciara; Savage, Hannah P; Tarajia, Musharaf; Rivera, René; Weeks‐Galindo, Cheyenne; Sambrano, Dilcia; Riley, Lee; Fernandez, Patricia L; Baumgarth, Nicole; Goodridge, Amador (2018-02-08)
      Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The cellular immune response to mycobacteria has been characterized extensively, but the antibody response remains underexplored. The present study ...
    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (American Journal of Respiratory and Critical Care Medicine, 2018-09-15)
      Tuberculosis (TB) remains the leading cause of death from a single infectious agent, followed by HIV/AIDS (1). Emerging countries, such as Panama, have not been able to curb TB infection rates. The development of novel ...
    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (2018-06-13)
      Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...