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Now showing items 11-20 of 31
New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases
(2014-07-17)
The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, e.g., oxidative ...
A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
(2014-10-11)
The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ...
Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants
(2014-04-08)
The use of spinal implants for spine fusion has been steadily increasing to avoid the risks of complications and donor site morbidity involved when using autologous bone. A variety of fusion cages are clinically available, ...
The lipid content and fatty acid composition of four eastern central Pacific native fish species
(2014-02-01)
Fish is an important source of nutritious n-3 fatty acids, which are necessary for the prevention of cardiovascular and neurological diseases. The lipid content and fatty acid composition of economically important fishes ...
Chemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass
(2014-03-04)
In screening for natural products with antiparasitic activity, an endophytic fungus, strain F2611, isolated from above-ground tissue of the tropical grass Paspalum conjugatum (Poaceae) in Panama, was chosen for bioactive ...
Malarial hemozoin: From target to tool
(2014-02-17)
Malaria is an extremely devastating disease that continues to affect millions of people each year. A distinctive attribute of malaria infected red blood cells is the presence of malarial pigment or the so-called hemozoin. ...
Sloth Hair as a Novel Source of Fungi with Potent AntiParasitic, Anti-Cancer and Anti-Bacterial Bioactivity
(2014-01-15)
The extraordinary biological diversity of tropical forests harbors a rich chemical diversity with enormous potential as a source of novel bioactive compounds. Of particular interest are new environments for microbial ...
Sloth Hair as a Novel Source of Fungi with Potent AntiParasitic, Anti-Cancer and Anti-Bacterial Bioactivity
(2014-01-15)
The extraordinary biological diversity of tropical forests harbors a rich chemical diversity with enormous potential as a source of novel bioactive compounds. Of particular interest are new environments for microbial ...
Revisiting Metal Toxicity in Neurodegenerative Diseases and Stroke: Therapeutic Potential
(2014-12-31)
Excessive accumulation of pro-oxidant metals, observed in affected brain regions, has consistently been implicated as a contributor to the brain pathology including neurodegenerative diseases and acute injuries such as ...
American Cutaneous Leishmaniasis in Panama: a historical review of entomological studies on anthropophilic Lutzomyia sand fly species
(2014-05-11)
We review existing information on the epidemiology of American Cutaneous Leishmaniasis (ACL) in Panama, with emphasis on the bionomics of anthropophilic Lutzomyia sand fly species. Evidence from Panamanian studies suggests ...