• English
    • español
  • English 
    • English
    • español
  • Login
View Item 
  •   DSpace Home
  • Investigación
  • Artículos Científicos
  • View Item
  •   DSpace Home
  • Investigación
  • Artículos Científicos
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Credneramides A and B: Neuromodulatory Phenethylamine and Isopentylamine Derivatives of a Vinyl Chloride-Containing Fatty Acid from cf. Trichodesmium sp. nov.

Thumbnail
View/Open
11. Credneramides J Nat Prod.pdf (323.8Kb)
Date
2011-12-12
Author
Malloy, Karla L.
Suyama, Takashi L.
Engene, Niclas
Debonsi, Hosana
Cao, Zhengyu
Matainaho, Teatulohi
Spadafora, Carmenza
Murray, Thomas F.
Gerwick, William H.
Metadata
Show full item record
Abstract
Credneramides A (1) and B (2), two vinyl chloride-containing metabolites, were isolated from a Papua New Guinea collection of cf. Trichodesmium sp. nov. and expand a recently described class of vinyl chloride-containing natural products. The precursor fatty acid, credneric acid (3), was isolated from both the aqueous and organic fractions of the parent fraction as well as from another geographically and phylogenetically distinct cyanobacterial collection (Panama). Credneramides A and B inhibited spontaneous calcium oscillations in murine cerebrocortical neurons at low micromolar concentrations (1, IC50 4.0 μM; 2, IC50 3.8 μM).
URI
http://repositorio-indicasat.org.pa/handle/123456789/48
Collections
  • Artículos Científicos

El enlace del OAI de este repositorio: www.repositorio-indicasat.org.pa/oai/request
Repositorio del Instituto de Investigaciones Científicas y Servicios de Alta Tecnología de Panamá (INDICASAT).
Utiliza DSpace copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback

 

 

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

View Usage Statistics

El enlace del OAI de este repositorio: www.repositorio-indicasat.org.pa/oai/request
Repositorio del Instituto de Investigaciones Científicas y Servicios de Alta Tecnología de Panamá (INDICASAT).
Utiliza DSpace copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback