Browsing by Title

Now showing items 143-162 of 227

    • Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice 

      Lax, Neil C.; Ahmed, Kh Tanvir; Ignatz, Christopher M.; Spadafora, Carmenza; Kolber, Benedict J.; Tidgewell, Kevin J. (2016-11-01)
      Marine cyanobacteria offer a robust resource for natural products drug discovery due to the secondary metabolites they produce. Objective—To identify novel cyanobacterial compounds that exhibit CNS psychoactive effects. ...

    • Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice 

      Lax, Neil C.; Ahmed, Kh Tanvir; Ignatz, Christopher M.; Spadafora, Carmenza; Kolber, Benedict J.; Tidgewell, Kevin J. (2016-11-08)
      Context—Marine cyanobacteria offer a robust resource for natural products drug discovery due to the secondary metabolites they produce. Objective—To identify novel cyanobacterial compounds that exhibit CNS psychoactive ...

    • A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 

      González, Yisett; Doens, Deborah; Cruz, Héctor; Santamaría, Ricardo; Gutiérrez, Marcelino; Llanes, Alejandro; Fernández, Patricia L. (2018-10-05)
      he proteasome is an intracellular complex that degrades damaged or unfolded proteins and participates in the regulation of several processes. The immunoproteasome is a specialized form that is expressed in response to ...

    • Maternal invasion history of Aedes aegypti and Aedes albopictus into the Isthmus of Panama: Implications for the control of emergent viral disease agents 

      Eskildsen, Gilberto A.; Loaiza, Jose R.; Smith, Octavio; Miller, Matthew J.; Bennet, Kelly L.; McMillan, W. Owen; Rovira, Jose R. (2018-03-26)
      Despite an increase in dengue outbreaks and the arrival of chikungunya and Zika disease in Panama, studies on the demographic history of the invasive Aedes mosquitoes that are the principle vectors of these diseases are ...

    • Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016 

      Fullman, Nancy; Yearwood, Jamal; Abay, Solomon M; Abbafati, Cristiana; Abd-Allah, Foad; Abdela, Jemal; Abdelalim, Ahmed; Abebe, Zegeye; Abuka Abebo, Teshome; Aboyans, Victor; Niguse Abraha, Haftom; Abreu, Daisy MX; Abu-Raddad, Laith J; Adane, Akilew Awoke; Adedoyin, Rufus Adesoji; Adetokunboh, Olatunji; Adhikari, Tara Ballav; Afarideh, Mohsen; Afshin, Ashkan; Agarwal, Gina; Agius, Dominic; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Eddine Aichour, Miloud Taki; Akibu, Mohammed; Akinyemi, Rufus Olusola; Akinyemiju, Tomi F; Akseer, Nadia; Al Lami, Faris Hasan; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Tahiya; Alasfoor, Deena; Albittar, Mohammed I; Addis Alene, Kefyalew; Al-Eyadhy, Ayman; Ali, Syed Danish; Alijanzadeh, Mehran; Aljunid, Syed M; Alkerwi, Ala'a; Alla, François; Allebeck, Peter; Allen, Christine; Alomari, Mahmoud A; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A; Alvis-Guzman, Nelson; Amare, Azmeraw T; Amenu, Kebede; Ammar, Walid; Ampem Amoako, Yaw; Anber, Nahla; Andrei, Catalina Liliana; Androudi, Sofia; T Antonio, Carl Abelardo; Araújo, Valdelaine EM; Aremu, Olatunde; Ärnlöv, Johan; Artaman, Al; Aryal, Krishna Kumar; Asayesh, Hamid; Tsegay Asfaw, Ephrem; Weldegebreal Asgedom, Solomon; Asghar, Rana Jawad; Ashebir, Mengistu Mitiku; Abera Asseffa, Netsanet; Atey, Tesfay Mehari; Atre, Sachin R; Atteraya, Madhu S; Avila-Burgos, Leticia; Arthur Avokpaho, Euripide Frinel G; Awasthi, Ashish; Ayala Quintanilla, Beatriz Paulina; Alebel Ayalew, Animut; Ayele, Henok Tadesse; Ayer, Rakesh; Betrand Ayuk, Tambe; Azzopardi, Peter; Azzopardi-Muscat, Natasha; Babalola, Tesleem Kayode; Badali, Hamid; Badawi, Alaa; Banach, Maciej; Banerjee, Amitava; Banstola, Amrit; Barber, Ryan M; Barboza, Miguel A; Barker-Collo, Suzanne L; Bärnighausen, Till; Barquera, Simon; Barrero, Lope H; Bassat, Quique; Basu, Sanjay; Baune, Bernhard T; Bazargan-Hejazi, Shahrzad; Bedi, Neeraj; Beghi, Ettore; Behzadifar, Masoud; Behzadifar, Meysam; Bekele, Bayu Begashaw; Belachew, Abate Bekele; Belay, Saba Abraham; Abebe Belay, Yihalem; Bell, Michelle L; Bello, Aminu K; Bennett, Derrick A; Bennett, James R; Bensenor, Isabela M; Berhe, Derbew Fikadu; Bernabé, Eduardo; Bernstein, Robert Steven; Beuran, Mircea; Bhalla, Ashish; Bhatt, Paurvi; Bhaumik, Soumyadeep; Bhutta, Zulfiqar A; Biadgo, Belete; Bijani, Ali; Bikbov, Boris; Birungi, Charles; Biryukov, Stan; Bizuneh, Hailemichael; Bolliger, Ian W; Bolt, Kaylin; Bou-Orm, Ibrahim R; Bozorgmehr, Kayvan; Brady, Oliver Jerome; Brazinova, Alexandra; Breitborde, Nicholas JK; Brenner, Hermann; Britton, Gabrielle; Brugha, Traolach S; Butt, Zahid A; Cahuana-Hurtado, Lucero; Campos-Nonato, Ismael Ricardo; Campuzano, Julio Cesar; Car, Josip; Car, Mate; Cárdenas, Rosario; Carrero, Juan Jesus; Carvalho, Felix; Castañeda-Orjuela, Carlos A; Castillo Rivas, Jacqueline; Catalá-López, Ferrán; Cercy, Kelly; Chalek, Julian; Chang, Hsing-Yi (2018-06-02)
      Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered ...

    • Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016 

      Fullman, Nancy; Barber, Ryan M; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Suliankatchi Abdulkader, Rizwan; Abdulle, Abdishakur M; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J; Abu-Rmeileh, Niveen ME; Adedeji, Isaac Akinkunmi; Adetokunboh, Olatunji; Afshin, Ashkan; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Eddine Aichour, Miloud Taki; Aichour, Amani Nidhal; Aichour, Ibtihel; Aiyar, Sneha; Akinyemi, Rufus Olusola; Akseer, Nadia; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alasfoor, Deena; Alene, Kefyalew Addis; Alizadeh-Navaei, Reza; Alkerwi, Ala'a; Alla, François; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A; Alvis-Guzman, Nelson; Amare, Azmeraw T; Amini, Erfan; Ammar, Walid; Ansari, Hossein; T Antonio, Carl Abelardo; Anwari, Palwasha; Arora, Megha; Artaman, Al; Aryal, Krishna Kumar; Asayesh, Hamid; Weldegebreal Asgedom, Solomon; Assadi, Reza; Atey, Tesfay Mehari; Atre, Sachin R; Avila-Burgos, Leticia; Arthur Avokpaho, Euripide Frinel G; Awasthi, Ashish; Azzopardi, Peter; Bacha, Umar; Badawi, Alaa; Balakrishnan, Kalpana; Bannick, Marlena S; Barac, Aleksandra; Barker-Collo, Suzanne L; Bärnighausen, Till; Barrero, Lope H; Basu, Sanjay; Battle, Katherine E; Baune, Bernhard T; Beardsley, Justin; Bedi, Neeraj; Beghi, Ettore; Béjot, Yannick; Bell, Michelle L; Bennett, Derrick A; Bennett, James R; Bensenor, Isabela M; Berhane, Adugnaw; Berhe, Derbew Fikadu; Bernabé, Eduardo; Demtsu Betsu, Balem; Beuran, Mircea; Beyene, Addisu Shunu; Bhala, Neeraj; Bhansali, Anil; Bhatt, Samir; Bhutta, Zulfiqar A; Bicer, Burcu Kucuk; Haghparast Bidgoli, Hassan; Bikbov, Boris; Bilal, Arebu I; Birungi, Charles; Biryukov, Stan; Bizuayehu, Habtamu Mellie; Blosser, Christopher D; Boneya, Dube Jara; Bose, Dipan; Bou-Orm, Ibrahim R; Brauer, Michael; Breitborde, Nicholas JK; Brugha, Traolach S; Bulto Bulto, Lemma Negesa; Butt, Zahid A; Cahuana-Hurtado, Lucero; Cameron, Ewan; Campuzano, Julio Cesar; Carabin, Hélène; Cárdenas, Rosario; Carrero, Juan Jesus; Carter, Austin; Casey, Daniel C; Castañeda-Orjuela, Carlos A; Castro, Ruben Estanislao; Catalá-López, Ferrán; Cercy, Kelly; Chang, Hsing-Yi; Chang, Jung-Chen; Charlson, Fiona J; Chew, Adrienne; Chisumpa, Vesper Hichilombwe; Chitheer, Abdulaal A; Christensen, Hanne; Christopher, Devasahayam Jesudas; Cirillo, Massimo; Cooper, Cyrus; Criqui, Michael H; Cromwell, Elizabeth A; Crump, John A; Dandona, Lalit; Dandona, Rakhi; Dargan, Paul I; Neves, José das; Davitoiu, Dragos V; de Courten, Barbora; De Steur, Hans; Kuate Defo, Barthelemy; Degenhardt, Louisa; Deiparine, Selina; Deribe, Kebede; Gabrielle, A deVeber; Ding, Eric L; Djalalinia, Shirin; Phuc Do, Huyen; Dokova, Klara; Doku, David Teye; Donkelaar, Aaron van; Ray Dorsey, E; Driscoll, Tim R; Dubey, Manisha (2017-09-16)
      Background The UN’s Sustainable Development Goals (SDGs) are grounded in the global ambition of “leaving no one behind”. Understanding today’s gains and gaps for the health-related SDGs is essential for decision makers as ...

    • Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017 

      Lozano, Rafael; Fullman, Nancy; Abate, Degu; Abay, Solomon M; Abbafati, Cristiana; Abbasi, Nooshin; Abbastabar, Hedayat; Abd-Allah, Foad; Abdela, Jemal; Abdelalim, Ahmed; Abdel-Rahman, Omar; Abdi, Alireza; Abdollahpour, Ibrahim; Suliankatchi Abdulkader, Rizwan; Dereje Abebe, Nebiyu; Abebe, Zegeye; Negesse Abejie, Ayenew; Abera, Semaw F; Zewdie Abil, Olifan; Aboyans, Victor; Abraha, Haftom Niguse; Abrham, Aklilu Roba; Abu-Raddad, Laith Jamal; Abu-Rmeileh, Niveen Me; Abyu, Gebre Y; Kokou Accrombessi, Manfred Mario; Acharya, Dilaram; Acharya, Pawan; Adamu, Abdu A; Adebayo, Oladimeji M; Adedeji, Isaac Akinkunmi; Adedoyin, Rufus Adesoji; Adekanmbi, Victor; Adetokunboh, Olatunji O; Adhena, Beyene Meressa; Adhikari, Tara Ballav; Adib, Mina G; Kouablan Adou, Arsène; Adsuar, Jose C; Afarideh, Mohsen; Afshari, Mahdi; Afshin, Ashkan; Agarwal, Gina; Aghayan, Sargis Aghasi; Agius, Dominic; Agrawal, Anurag; Agrawal, Sutapa; Ahmadi, Alireza; Ahmadi, Mehdi; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Ahmed, Sayem; Yihunie Akalu, Temesgen; Akanda, Ali S; Akbari, Mohammad Esmaeil; Akibu, Mohammed; Akinyemi, Rufus Olusola; Akinyemiju, Tomi; Akseer, Nadia; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Tahiya; Albujeer, Ammar; Alebel, Animut; Alene, Kefyalew Addis; Al-Eyadhy, Ayman; Alhabib, Samia; Ali, Raghib; Alijanzadeh, Mehran; Alizadeh-Navaei, Reza; Aljunid, Syed Mohamed; Alkerwi, Ala'a; Alla, François; Allebeck, Peter; Allen, Christine A; Almasi, Ali; Al-Maskari, Fatma; Al-Mekhlafi, Hesham M; Alonso, Jordi; Al-Raddadi, Rajaa M; Alsharif, Ubai; Altirkawi, Khalid; Alvis-Guzman, Nelson; Amare, Azmeraw T; Amenu, Kebede; Amini, Erfan; Ammar, Walid; Anber, Nahla Hamed; Anderson, Jason A; Andrei, Catalina Liliana; Androudi, Sofia; Animut, Megbaru Debalkie; Anjomshoa, Mina; Ansari, Hossein; Ansariadi, Ansariadi; Geleto Ansha, Mustafa; T Antonio, Carl Abelardo; Anwari, Palwasha; Appiah, Lambert Tetteh; Aremu, Olatunde; Abera Areri, Habtamu; Ärnlöv, Johan; Arora, Monika; Aryal, Krishna K; Asayesh, Hamid; Asfaw, Ephrem Tsegay; Weldegebreal Asgedom, Solomon; Asghar, Rana Jawad; Assadi, Reza; Ataro, Zerihun; Atique, Suleman; Atre, Sachin R; Atteraya, Madhu Sudhan; Ausloos, Marcel; Avila-Burgos, Leticia; Avokpaho, Euripide FGA; Awasthi, Ashish; Ayala Quintanilla, Beatriz Paulina; Ayele, Henok Tadesse; Ayele, Yohanes; Ayer, Rakesh; Azarpazhooh, Mahmoud Reza; Azzopardi, Peter S; Azzopardi-Muscat, Natasha; Babalola, Tesleem Kayode; Babazadeh, Arefeh; Badali, Hamid; Badawi, Alaa; Balakrishnan, Kalpana; Bali, Ayele Geleto; Banach, Maciej; Banerjee, Amitava; Mattar Banoub, Joseph Adel; Banstola, Amrit; Barac, Aleksandra; Barboza, Miguel A; Barker-Collo, Suzanne Lyn; Bärnighausen, Till Winfried; Barrero, Lope H; Barthelemy, Celine M; Bassat, Quique; Basu, Arindam; Basu, Sanjay; Battista, Robert J; Baune, Bernhard T; Wondifraw Baynes, Habtamu; Bazargan-Hejazi, Shahrzad; Bedi, Neeraj; Beghi, Ettore (2018-11-10)
      Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver ...

    • Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 

      Lim, Stephen S; Allen, Kate; Bhutta, Zulfiqar A; Dandona, Lalit; Forouzanfar, Mohammad H; Fullman, Nancy; Gething, Peter W; Goldberg, Ellen M; Hay, Simon I; Holmberg, Mollie; Kinfu, Yohannes; Kutz, Michael J; Larson, Heidi J; Liang, Xiaofeng; Lopez, Alan D; Lozano, Rafael; McNellan, Claire R; Mokdad, Ali H; Mooney, Meghan D; Naghavi, Mohsen; Olsen, Helen E; Pigott, David M; Salomon, Joshua A; Vos, Theo; Wang, Haidong; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Abdulle, Abdishakur M; Abraham, Biju; Abubakar, Ibrahim; Abu-Raddad, Laith J; Abu-Rmeileh, Niveen ME; Yitayih Abyu, Gebre; Achoki, Tom; Adebiyi, Akindele Olupelumi; Adedeji, Isaac Akinkunmi; Agbelenko Afanvi, Kossivi; Afshin, Ashkan; Agarwal, Arnav; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Kedir Yimam; Akanda, Ali Shafqat; Akinyemi, Rufus Olusola; Akinyemiju, Tomi F; Akseer, Nadia; Al-Aly, Ziyad; Alam, Khurshid; Alam, Uzma; Alasfoor, Deena; AlBuhairan, Fadia S; Aldhahri, Saleh Fahed; Aldridge, Robert William; Alemu, Zewdie Aderaw; Ali, Raghib; Alkerwi, Ala'a; Alkhateeb, Mohammad AB; Alla, François; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A; Alvarez Martin, Elena; Alvis-Guzman, Nelson; Amare, Azmeraw T; Amberbir, Alemayehu; Amegah, Adeladza Kofi; Amini, Heresh; Ammar, Walid; Amrock, Stephen Marc; Andersen, Hjalte H; Anderson, Benjamin O; Anderson, Gregory M; T Antonio, Carl Abelardo; Anwari, Palwasha; Ärnlöv, Johan; Artaman, Al; Asayesh, Hamid; Jawad Asghar, Rana; Atique, Suleman; Arthur Avokpaho, Euripide Frinel G; Awasthi, Ashish; Ayala Quintanilla, Beatriz Paulina; Azzopardi, Peter; Bacha, Umar; Badawi, Alaa; Balakrishnan, Kalpana; Banerjee, Amitava; Barac, Aleksandra; Barber, Ryan; Barker-Collo, Suzanne L; Bärnighausen, Till; Barrero, Lope H; Barrientos-Gutierrez, Tonatiuh; Basu, Sanjay; Bayou, Tigist Assefa; Bazargan-Hejazi, Shahrzad; Beardsley, Justin; Bedi, Neeraj; Beghi, Ettore; Béjot, Yannick; Bell, Michelle L; Bello, Aminu K; Bennett, Derrick A; Bensenor, Isabela M; Benzian, Habib; Berhane, Adugnaw; Bernabé, Eduardo; Bernal, Oscar Alberto; Demtsu Betsu, Balem; Beyene, Addisu Shunu; Bhala, Neeraj; Bhatt, Samir; Biadgilign, Sibhatu; Bienhoff, Kelly A; Bikbov, Boris; Binagwaho, Agnes; Bisanzio, Donal; Bjertness, Espen; Blore, Jed; Bourne, Rupert RA; Brainin, Michael; Brauer, Michael; Brazinova, Alexandra; Breitborde, Nicholas JK; Broday, David M; Brugha, Traolach S; Buchbinder, Rachelle; Butt, Zahid A; Cahill, Leah E; Campos-Nonato, Ismael Ricardo; Campuzano, Julio Cesar; Carabin, Hélène; Cárdenas, Rosario; Carrero, Juan Jesus; Carter, Austin; Casey, Daniel; Caso, Valeria; Castañeda-Orjuela, Carlos A; Castillo Rivas, Jacqueline; Catalá-López, Ferrán; Cavalleri, Fiorella; Cecílio, Pedro; Chang, Hsing-Yi; Chang, Jung-Chen (2016-10-08)
      In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 ...

    • Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β‑Amino Acids 

      Fenner, Amanda M.; Engene, Niclas; Spadafora, Carmenza; Gerwick, William H.; Balunas, Marcy J. (2016-01-19)
      From a collection of marine cyanobacteria made in the Coiba National Park along the Pacific coast of the Republic of Panama a novel cyclic depsipeptide, given the trivial name medusamide A, has been isolated and fully ...

    • Mitogenomics of Central American weakly-electric fishes 

      Aguilar, Celestino; Miller, Matthew J.; Loaiza, Jose R.; Krahe, Rüdiger; De León, Luis F. (2019-02-20)
      Electric fishes are a diverse group of freshwater organisms with the ability to generate electric organ discharges (EODs) that are used for communication and electrolocation. This group (ca. 200 species) has originated in ...

    • Molecular Ecological Insights into Neotropical Bird–Tick Interactions 

      Miller1, Matthew J.; Loaiza, Jose R.; Herre, Edward Allen; Aguilar, Celestino; Quintero, Diomedes; Alvarez, Eric; Bermingham, Eldredge; Esser, Helen J. (2016-05-20)
      In the tropics, ticks parasitize many classes of vertebrate hosts. However, because many tropical tick species are only identifiable in the adult stage, and these adults usually parasitize mammals, most attention on the ...

    • Molecular validation of anthropophilic Phlebotominae sandflies (Diptera: Psychodidae) in Central Panama 

      Dutar, Larissa; Loaiza, Jose R. (2019-08-15)
      Six Phlebotominae sand fly species are incriminated as biological vectors of human pathogens in Panama, but molecular corroboration is still needed. We aim at confirming the identity of Phlebotominae species documented as ...

    • Mosquito-Host Interactions during and after an Outbreak of Equine Viral Encephalitis in Eastern Panama 

      Navia-Gine, Wayra G.; Loaiza, Jose R.; Miller, Matthew J. (2013-12-10)
      Mosquito blood meals provide information about the feeding habits and host preference of potential arthropod-borne disease vectors. Although mosquito-borne diseases are ubiquitous in the Neotropics, few studies in this ...

    • Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects 

      Mitra, Joy; Guerrero, Erika N; Hegde, Pavana M; Liachko, Nicole F; Wang, Haibo; Vasquez, Velmarini; Gao, Junling; Pandey, Arvind; Taylor, J Paul; Kraemer, Brian C; Wu, Ping; Boldogh, Istvan; Garruto, Ralph M; Mitra, Sankar; Rao, KS Jagannatha; Hegde, Muralidhar L (2019-03-05)
      Genome damage and their defective repair have been etiologically linked to degenerating neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the specific mechanisms remain enigmatic. The ...

    • A multi-faceted genotoxic network of alpha-synuclein in the nucleus and mitochondria of dopaminergic neurons in Parkinson’s disease: Emerging concepts and challenges 

      Vasquez, Velmarini; Mitra, Joy; Wang, Haibo; Hegde, Pavana M; Rao, KS Jagannatha; Hegde, Muralidhar L (2020-02-01)
      α-Synuclein is a hallmark amyloidogenic protein component of the Lewy bodies (LBs) present in dopaminergic neurons affected by Parkinson’s disease (PD). Despite an enormous increase in emerging knowledge, the mechanism(s) ...

    • A Multicomponent Animal Virus Isolated from Mosquitoes 

      Ladner, Jason T.; Wiley, Michael R.; Beitzel, Brett; Auguste, Albert J.; Dupuis, Alan P.; Lindquist, Michael E.; Sibley, Samuel D.; Kota, Krishna P.; Fettere, David; Eastwood, Gillian; Kimme, David; Prieto, Karla; Guzman, Hilda; Aliota, Matthew T.; Reyes, Daniel; Brueggemann, Ernst E.; John, Lena St.; Hyeroba, David; Lauck, Michael; Friedrich, Thomas C.; O’Connor, David H.; Gestole, Marie C.; Cazares, Lisa H.; Popov, Vsevolod L.; Castro-Llanos, Fanny; Kochel, Tadeusz J.; Kenny, Tara; White, Bailey; Ward, Michael D.; Loaiza, Jose R.; Goldberg, Tony L.; Weaver, Scott C.; Kramer, Laura D.; Tesh, Robert B.; Palacios, Gustavo (2016-09-14)
      RNA viruses exhibit a variety of genome organization strategies, including multicomponent genomes in which each segment is packaged separately. Although multicomponent genomes are common among viruses infecting plants and ...

    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (American Journal of Respiratory and Critical Care Medicine, 2018-09-15)
      Tuberculosis (TB) remains the leading cause of death from a single infectious agent, followed by HIV/AIDS (1). Emerging countries, such as Panama, have not been able to curb TB infection rates. The development of novel ...

    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (2018-06-13)
      Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...

    • Mycobacterium bovis in Panama, 2013 

      Acosta, Fermín; Chernyaeva, Ekatherina; Mendoza, Libardo; Sambrano, Dilcia; Correa, Ricardo; Rotkevich, Mikhail; Tarté, Miroslava; Hernández, Humberto; Velazco, Bredio; de Escobar, Cecilia; H. de Waard, Jacobus; Goodridge, Amador (2015-06-01)
      Panama remains free of zoonotic tuberculosis caused by Mycobacterium bovis. However, DNA fingerprinting of 7 M. bovis isolates from a 2013 bovine tuberculosis outbreak indicated minimal homology with strains previously ...

    • Mycobacterium tuberculosis Isolates from Single Outpatient Clinic in Panama City Exhibit Wide Genetic Diversity 

      Sambrano, Dilcia; Correa, Ricardo; Almengor, Pedro; Domínguez, Amada; Vega, Silvio; Goodridge, Amador (2014-08-06)
      Understanding Mycobacterium tuberculosis biodiversity and transmission is significant for tuberculosis control. This short report aimed to determine the genetic diversity of M. tuberculosis isolates from an outpatient ...