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Now showing items 176-195 of 227

    • Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes 

      Awandarea, Gordon A.; Spadafora, Carmenza; Mocha, J. Kathleen; Duttaa, Sheetij; Haynesa, J. David; Stoutea, José A. (2011-05-18)
      AmajorityofPlasmodiumfalciparumstrainsinvadeerythrocytesthroughinteractionswithsialicacid(SA) on glycophorins. However, we recently reported that complement receptor 1 (CR1) is a SA-independent invasionreceptorofmanylabo ...

    • Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017 

      Murray, Christopher JL; Callender, Charlton SKH; Kulikoff, Xie Rachel; Srinivasan, Vinay; Abate, Degu; Hassen Abate, Kalkidan; Abay, Solomon M; Abbasi, Nooshin; Abbastabar, Hedayat; Abdela, Jemal; Abdelalim, Ahmed; Abdel-Rahman, Omar; Abdi, Alireza; Abdoli, Nasrin; Abdollahpour, Ibrahim; Abdulkader, Rizwan Suliankatchi; Abebe, Haftom Temesgen; Abebe, Molla; Abebe, Zegeye; Abuka Abebo, Teshome; Negesse Abejie, Ayenew; Aboyans, Victor; Abraha, Haftom Niguse; Xavier Abreu, Daisy Maria; Abrham, Aklilu Roba; Abu-Raddad, Laith Jamal; Abu-Rmeileh, Niveen ME; Kokou Accrombessi, Manfred Mario; Acharya, Pawan; Adamu, Abdu A; Adebayo, Oladimeji M; Adedeji, Isaac Akinkunmi; Adekanmbi, Victor; Adetokunboh, Olatunji O; Meressa Adhena, Beyene; Adhikari, Tara Ballav; Adib, Mina G; Kouablan Adou, Arsène; Adsuar, Jose C; Afarideh, Mohsen; Afshin, Ashkan; Agarwal, Gina; Agesa, Kareha M; Aghayan, Sargis Aghasi; Agrawal, Sutapa; Ahmadi, Alireza; Ahmadi, Mehdi; Ahmed, Muktar Beshir; Ahmed, Sayem; Aichour, Amani Nidhal; Aichour, Ibtihel; Eddine Aichour, Miloud Taki; Akanda, Ali S; Akbari, Mohammad Esmaeil; Akibu, Mohammed; Akinyemi, Rufus Olusola; Akinyemiju, Tomi; Akseer, Nadia; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alebel, Animut; Aleman, Alicia V; Addis Alene, Kefyalew; Al-Eyadhy, Ayman; Ali, Raghib; Alijanzadeh, Mehran; Alizadeh-Navaei, Reza; Aljunid, Syed Mohamed; Alkerwi, Ala'a; Alla, François; Allebeck, Peter; Almasi, Ali; Alonso, Jordi; Al-Raddadi, Rajaa M; Alsharif, Ubai; Altirkawi, Khalid; Alvis-Guzman, Nelson; Amare, Azmeraw T; Ammar, Walid; Hamed Anber, Nahla; Andrei, Catalina Liliana; Androudi, Sofia; Animut, Megbaru Debalkie; Ansari, Hossein; Ansha, Mustafa Geleto; T Antonio, Carl Abelardo; Yaw Appiah, Seth Christopher; Aremu, Olatunde; Abera Areri, Habtamu; Arian, Nicholas; Ärnlöv, Johan; Artaman, Al; Aryal, Krishna K; Asayesh, Hamid; Asfaw, Ephrem Tsegay; Weldegebreal Asgedom, Solomon; Assadi, Reza; Mehari Atey, Tesfay Mehari; Atique, Suleman; Atteraya, Madhu Sudhan; Ausloos, Marcel; Avokpaho, Euripide FGA; Awasthi, Ashish; Ayala Quintanilla, Beatriz Paulina; Ayele, Yohanes; Ayer, Rakesh; Ayuk, Tambe B; Azzopardi, Peter S; Babalola, Tesleem Kayode; Babazadeh, Arefeh; Badali, Hamid; Badawi, Alaa; Bali, Ayele Geleto; Banach, Maciej; Barker-Collo, Suzanne Lyn; Bärnighausen, Till Winfried; Barrero, Lope H; Basaleem, Huda; Bassat, Quique; Basu, Arindam; Baune, Bernhard T; Wondifraw Baynes, Habtamu; Beghi, Ettore; Behzadifar, Masoud; Behzadifar, Meysam; Bekele, Bayu Begashaw; Belachew, Abate Bekele; Gebreyesus Belay, Aregawi; Belay, Ezra; Belay, Saba Abraham; Belay, Yihalem Abebe; Bell, Michelle L; Bello, Aminu K; Bennett, Derrick A; Bensenor, Isabela M; Bergeron, Gilles; Berhane, Adugnaw; Berman, Adam E; Bernabe, Eduardo; Bernstein, Robert S; Bertolacci, Gregory J; Beuran, Mircea; Bhattarai, Suraj; Bhaumik, Soumyadeep; Bhutta, Zulfiqar A; Biadgo, Belete; Bijani, Ali; Bikbov, Boris; Bililign, Nigus (2018-11-10)
      Background Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates ...

    • Production of pullulan using jaggery as substrate by Aureobasidium pullulans MTCC 2195 

      Ganduri, VS; Rao, KS Jagannatha; Mangamuri, Usha Kiranmayi; Lakahmi, Vijaya M; Poda, Sudhakar (2016-04-01)
      Shake-flask fermentation, under batch cultivation, was investigated for the production of fungal exopolysaccharide, pullulan using jaggery (a traditional concentrated sugar cane juice) as a carbon substrate by Aureobasidium ...

    • Proteomic fingerprint identification of Neotropical hard tick species (Acari: Ixodidae) using a self-curated mass spectra reference library 

      Gittens, Rolando A.; Almanza, Alejandro; Álvarez, Eric; Bennett, Kelly L.; Mejía, Luis C.; Sanchez-Galan, Javier E.; Merchan, Fernando; Kern, Jonathan; Miller, Matthew J.; Esser, Helen J.; Hwang, Robert; Dong, May; De León, Luis F.; Loaiza, Jose R. (2020-04-14)
      Matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry is an analytical method that detects macromolecules that can be used as biomarkers for taxonomic identification in arthropods. The ...

    • A Pseudopterane Diterpene Isolated From the Octocoral Pseudopterogorgia acerosa Inhibits the Inflammatory Response Mediated by TLR-Ligands and TNF-Alpha in Macrophages 

      González, Yisett; Doens, Deborah; Santamaría, Ricardo; Ramos, Marla; Restrepo, Carlos M.; Barros de Arruda, Luciana; Lleonart, Ricardo; Gutiérrez, Marcelino; Fernández, Patricia L. (2013-12-16)
      Several diterpenoids isolated from terrestrial and marine environments have been identified as important anti-inflammatory agents. Although considerable progress has been made in the area of anti-inflammatory treatment, ...

    • Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum 

      Torres-Mendoza, Daniel; Coronado, Lorena M.; Pineda, Laura M.; Guzmán, Héctor M.; Dorrestein, Pieter C.; Spadafora, Carmenza; Gutiérrez, Marcelino (2018-08-29)
      Chemical examination of the octocoral-associated Bacillus species (sp.) DT001 led to the isolation of pumilacidins A (1) and C (2). We investigated the effect of these compounds on the viability of Plasmodium falciparum ...

    • Randomized, Double-Blinded, Phase 2 Trial of WR 279,396 (Paromomycin and Gentamicin) for Cutaneous Leishmaniasis in Panama 

      Sosa, Nestor; Capitan, Zeus; Nieto, Javier; Nieto, Melissa; Calzada, Jose; Paz, Hector; Spadafora, Carmenza; Kreishman, Mara Deitric; Kopydlowski, Karen; Ullman, Diane; McCarthy, William F.; Ransom, Janet; Berman, Jhonathan; Scott, Charles; Grogl, Max (2013-07-15)
      In this randomized, double-blinded Phase 2 trial, 30 patients with Leishmania panamensis cutaneous leishmaniasis were randomly allocated (1:1) to receive once daily topical treatment with WR 279,396 (15% paromomycin + 0.5% ...

    • Randomized, Double-Blinded, Phase 2 Trial of WR 279,396 (Paromomycin and Gentamicin) for Cutaneous Leishmaniasis in Panama 

      Sosa, Nestor; Capitan, Zeuz; Nieto, Javier; Nieto, Melissa; Calzada, Jose; Paz, Hector; Spadafora, Carmenza; Kreishman-Deitrick, Mara; Kopydlowski, Karen; Ullman, Diane; McCarthy, William F.; Ransom, Janet; Berman, Jonathan; Scott, Charles; Grogl, Max (2013-07-15)
      In this randomized, double-blinded Phase 2 trial, 30 patients with Leishmania panamensis cutaneous leishmaniasis were randomly allocated (1:1) to receive once daily topical treatment with WR 279,396 (15% paromomycin + 0.5% ...

    • Randomized, Double-Blinded, Phase 2 Trial of WR 279,396 (Paromomycin and Gentamicin) for Cutaneous Leishmaniasis in Panama 

      Sosa, Nestor; Capitan, Zeus; Nieto, Javier; Nieto, Melissa; Calzada, Jose; Paz, Hector; Spadafora, Carmenza; Kreishman, Mara Deitric; Kopydlowski, Karen; Ullman, Diane; McCarthy, William F.; Ransom, Janet; Berman, Jonathan; Scott, Charles; Grogl, Max (2013-07-15)
      In this randomized, double-blinded Phase 2 trial, 30 patients with Leishmania panamensis cutaneous leishmaniasis were randomly allocated (1:1) to receive once daily topical treatment with WR 279,396 (15% paromomycin + 0.5% ...

    • Recommendations of generic names in Diaporthales competing for protection or use. 

      Rossman, AY.; Adams, GC.; Cannon, PF.; Castlebury, LA.; Crous, PW.; Gryzenhout, M.; Jaklitsch, WM.; Mejía, Luis Carlos; Stoykov, D.; Udayanga, D.; Voglmayr, H.; Walker, DM. (2015-06-04)
      In advancing to one name for fungi, this paper treats generic names competing for use in the order Diaporthales (Ascomycota, Sordariomycetes) and makes a recommendation for the use or protection of one generic name among ...

    • Reduced Food Intake Among Tuberculosis Patients Within an Urban Setting in Panama (P10-023-19) 

      Cubilla, Idalina; Rios, Maritza; Batista, Victoria; Rosero, Sara; Sambrano, Dilcia; Castillo, Juan; Colon-Ramos, Uriyoan; Cleary, Sean D; Goodridge, Amador; Luque, Odemaris; de Simmons, Isolina; de Chavez, Ana; Cuadra, Yaracelys; Jurado, Julio; Gonzalez, Rolando; Williams, Victoria (2019-06-01)
      Objectives The aim of our study is to characterize the dietary factors and food items intake of people living with pulmonary tuberculosis in an urban and high disease incidence city in Panama. Methods We recruited 41 ...

    • Regulating in vivo calcification of alginate microbeads 

      S.D. Lee, Christopher; Moyer, Hunter R.; Gittens I, Rolando A.; Williams, Joseph K.; Boskey, Adele L.; Boyan, Barbara D.; Schwartz, Zvi (2010-04-02)
      Alginate calcification has been previously reported clinically and during animal implantation; however no study has investigated the mechanism, extensively characterized the mineral, or evaluated multiple methods to regulate ...

    • Relación entre las funciones ejecutivas y el rendimiento académico en una muestra de escolares 

      Flores, Julio; Pérez, Ambar; Oviedo, Diana; Britton, Gabrielle B; Mojica, Marita (2020-07-30)
      En la última década, la integración entre las neurociencias y la educación hacontribuido a la comprensión y mejoramiento del sistema educativo, además, se ha mostrado un interés en el estudio de las funciones ejecutivas y ...

    • A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods 

      Madrigal, Marialaura; Rao, KS Jagannatha; Riordan, Neil H (2014-10-11)
      The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ...

    • A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods 

      Madrigal, Marialaura; S Rao, Kosagisharaf; H. Riordan, Neil (Madrigal et al. Journal of Translational Medicine, 2014-10-11)
      The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ...

    • A review on the wettability of dental implant surfaces I: Theoretical and experimental aspects 

      Rupp, Frank; Gittens, Rolando A.; Scheideler, Lutz; Marmur, Abraham; Boyan, Barbara D.; Schwartz, Zvi; Geis-Gerstorfer, Jürgen (2014-02-28)
      The surface wettability of biomaterials determines the biological cascade of events at the biomaterial/ host interface. Wettability is modulated by surface characteristics, such as surface chemistry and surface topography. ...

    • A review on the wettability of dental implant surfaces II: Biological and clinical aspects 

      Gittens, Rolando A.; Scheideler, Lutz; Rupp, Frank; Hyzy, Sharon L.; Geis-Gerstorfer, Jürgen; Schwartz, Zvi; Boyan, Barbara D. (2014-04-05)
      Dental and orthopedic implants have been under continuous advancement to improve their interactions with bone and ensure a successful outcome for patients. Surface characteristics such as surface topography and surface ...

    • Revisión de Modelos Hiperelásticos utilizados en Tejidos 

      Moreno, Miguel; Plazaola, Carlos; González, Guadalupe; Zambrano, Mayteé; Spadafora, Carmenza (2018-02-04)
      This work is related to the hyperelastic models most used in soft tissue. The importance of obtaining accurate mechanical properties of tissues are of great interest for various medical applications, for example: in treatment ...

    • Revisión de Modelos Hiperelásticos utilizados en Tejidos 

      Moreno, Miguel; Plazaola, Carlos; González, Guadalupe; Zambrano, Mayteé; Spadafora, Carmenza (2018-02-04)
      This work is related to the hyperelastic models most used in soft tissue. The importance of obtaining accurate mechanical properties of tissues are of great interest for various medical applications, for example: in treatment ...

    • Revisiting Metal Toxicity in Neurodegenerative Diseases and Stroke: Therapeutic Potential 

      Mitra, Joy; Vasquez, Velmarini; Hegde, Pavana M; Boldogh, Istvan; Mitra, Sankar; Kent, Thomas A; Rao, Kosagi S; L Hegde, Muralidhar (2014-12-31)
      Excessive accumulation of pro-oxidant metals, observed in affected brain regions, has consistently been implicated as a contributor to the brain pathology including neurodegenerative diseases and acute injuries such as ...