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Global, regional, and national burden of tuberculosis, 1990–2016: results from the Global Burden of Diseases, Injuries, and Risk Factors 2016 Study
(2018-12-01)
Background Although a preventable and treatable disease, tuberculosis causes more than a million deaths each year. As countries work towards achieving the Sustainable Development Goal (SDG) target to end the tuberculosis ...
Avian Mycobacteriosis in a Rescued Harpy Eagle from Darien Forest, Panama
(2019-11-08)
Background: The Harpy eagle (Harpia harpyia) is the largest raptor in the Neotropical region, distributed in low densities within primary forest habitats from southern Mexico to east-central Brazil, including Central America ...
Avian Mycobacteriosis in a Rescued Harpy Eagle from Darien Forest, Panama
(Acta Scientiae Veterinariae, 2019-06-20)
The Harpy eagle (Harpia harpyia) is the largest raptor in the Neotropical region, distributed in low densities within primary forest habitats from southern Mexico to east-central Brazil, including Central America and ...
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
(American Journal of Respiratory and Critical Care Medicine, 2018-09-15)
Tuberculosis (TB) remains the leading cause of death from a single infectious agent, followed by HIV/AIDS (1). Emerging countries, such as Panama, have not been able to curb TB infection rates. The development of novel ...
Storage in ultra-low-temperature decreases the levels of IgM anticardiolipin antibody in serum samples from tuberculosis patients
(2014-06-01)
The evaluation of novel tuberculosis (TB) biomarkers relies on analysis of previously stored sample sets. We aimed to determine the effect of storage temperature on serum IgM anticardiolipin antibody levels in samples from ...
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
(2018-06-13)
Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...
Reduced Food Intake Among Tuberculosis Patients Within an Urban Setting in Panama (P10-023-19)
(2019-06-01)
Objectives The aim of our study is to characterize the dietary factors and food items intake of people living with pulmonary tuberculosis in an urban and high disease incidence city in Panama. Methods We recruited 41 ...
Overweight, Obesity, and Older Age Favor Latent Tuberculosis Infection among Household Contacts in Low Tuberculosis-Incidence Settings within Panama
(2019-05-01)
Latent tuberculosis infection (LTBI) remains the main source of new active tuberculosis (TB) cases worldwide. Household close contacts (HCCs) are at high risk of acquiring LTBI and subsequent development of TB. In this ...
Mycobacterium tuberculosis Isolates from Single Outpatient Clinic in Panama City Exhibit Wide Genetic Diversity
(2014-08-06)
Understanding Mycobacterium tuberculosis biodiversity and transmission is significant for tuberculosis control. This short report aimed to determine the genetic diversity of M. tuberculosis isolates from an outpatient ...
Simplified Model to Survey Tuberculosis Transmission in Countries Without Systematic Molecular Epidemiology Programs
(Emerging Infectious Diseases, 2019-03-03)
Systematic molecular/genomic epidemiology studies for tuberculosis surveillance cannot be implemented in many countries. We selected Panama as a model for an alternative strategy. Mycobacterial interspersed repetitive ...