Browsing Artículos Científicos by Title

Now showing items 150-169 of 227

    • Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 

      Lim, Stephen S; Allen, Kate; Bhutta, Zulfiqar A; Dandona, Lalit; Forouzanfar, Mohammad H; Fullman, Nancy; Gething, Peter W; Goldberg, Ellen M; Hay, Simon I; Holmberg, Mollie; Kinfu, Yohannes; Kutz, Michael J; Larson, Heidi J; Liang, Xiaofeng; Lopez, Alan D; Lozano, Rafael; McNellan, Claire R; Mokdad, Ali H; Mooney, Meghan D; Naghavi, Mohsen; Olsen, Helen E; Pigott, David M; Salomon, Joshua A; Vos, Theo; Wang, Haidong; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Abdulle, Abdishakur M; Abraham, Biju; Abubakar, Ibrahim; Abu-Raddad, Laith J; Abu-Rmeileh, Niveen ME; Yitayih Abyu, Gebre; Achoki, Tom; Adebiyi, Akindele Olupelumi; Adedeji, Isaac Akinkunmi; Agbelenko Afanvi, Kossivi; Afshin, Ashkan; Agarwal, Arnav; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Kedir Yimam; Akanda, Ali Shafqat; Akinyemi, Rufus Olusola; Akinyemiju, Tomi F; Akseer, Nadia; Al-Aly, Ziyad; Alam, Khurshid; Alam, Uzma; Alasfoor, Deena; AlBuhairan, Fadia S; Aldhahri, Saleh Fahed; Aldridge, Robert William; Alemu, Zewdie Aderaw; Ali, Raghib; Alkerwi, Ala'a; Alkhateeb, Mohammad AB; Alla, François; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A; Alvarez Martin, Elena; Alvis-Guzman, Nelson; Amare, Azmeraw T; Amberbir, Alemayehu; Amegah, Adeladza Kofi; Amini, Heresh; Ammar, Walid; Amrock, Stephen Marc; Andersen, Hjalte H; Anderson, Benjamin O; Anderson, Gregory M; T Antonio, Carl Abelardo; Anwari, Palwasha; Ärnlöv, Johan; Artaman, Al; Asayesh, Hamid; Jawad Asghar, Rana; Atique, Suleman; Arthur Avokpaho, Euripide Frinel G; Awasthi, Ashish; Ayala Quintanilla, Beatriz Paulina; Azzopardi, Peter; Bacha, Umar; Badawi, Alaa; Balakrishnan, Kalpana; Banerjee, Amitava; Barac, Aleksandra; Barber, Ryan; Barker-Collo, Suzanne L; Bärnighausen, Till; Barrero, Lope H; Barrientos-Gutierrez, Tonatiuh; Basu, Sanjay; Bayou, Tigist Assefa; Bazargan-Hejazi, Shahrzad; Beardsley, Justin; Bedi, Neeraj; Beghi, Ettore; Béjot, Yannick; Bell, Michelle L; Bello, Aminu K; Bennett, Derrick A; Bensenor, Isabela M; Benzian, Habib; Berhane, Adugnaw; Bernabé, Eduardo; Bernal, Oscar Alberto; Demtsu Betsu, Balem; Beyene, Addisu Shunu; Bhala, Neeraj; Bhatt, Samir; Biadgilign, Sibhatu; Bienhoff, Kelly A; Bikbov, Boris; Binagwaho, Agnes; Bisanzio, Donal; Bjertness, Espen; Blore, Jed; Bourne, Rupert RA; Brainin, Michael; Brauer, Michael; Brazinova, Alexandra; Breitborde, Nicholas JK; Broday, David M; Brugha, Traolach S; Buchbinder, Rachelle; Butt, Zahid A; Cahill, Leah E; Campos-Nonato, Ismael Ricardo; Campuzano, Julio Cesar; Carabin, Hélène; Cárdenas, Rosario; Carrero, Juan Jesus; Carter, Austin; Casey, Daniel; Caso, Valeria; Castañeda-Orjuela, Carlos A; Castillo Rivas, Jacqueline; Catalá-López, Ferrán; Cavalleri, Fiorella; Cecílio, Pedro; Chang, Hsing-Yi; Chang, Jung-Chen (2016-10-08)
      In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 ...

    • Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β‑Amino Acids 

      Fenner, Amanda M.; Engene, Niclas; Spadafora, Carmenza; Gerwick, William H.; Balunas, Marcy J. (2016-01-19)
      From a collection of marine cyanobacteria made in the Coiba National Park along the Pacific coast of the Republic of Panama a novel cyclic depsipeptide, given the trivial name medusamide A, has been isolated and fully ...

    • Mitogenomics of Central American weakly-electric fishes 

      Aguilar, Celestino; Miller, Matthew J.; Loaiza, Jose R.; Krahe, Rüdiger; De León, Luis F. (2019-02-20)
      Electric fishes are a diverse group of freshwater organisms with the ability to generate electric organ discharges (EODs) that are used for communication and electrolocation. This group (ca. 200 species) has originated in ...

    • Molecular Ecological Insights into Neotropical Bird–Tick Interactions 

      Miller1, Matthew J.; Loaiza, Jose R.; Herre, Edward Allen; Aguilar, Celestino; Quintero, Diomedes; Alvarez, Eric; Bermingham, Eldredge; Esser, Helen J. (2016-05-20)
      In the tropics, ticks parasitize many classes of vertebrate hosts. However, because many tropical tick species are only identifiable in the adult stage, and these adults usually parasitize mammals, most attention on the ...

    • Molecular validation of anthropophilic Phlebotominae sandflies (Diptera: Psychodidae) in Central Panama 

      Dutar, Larissa; Loaiza, Jose R. (2019-08-15)
      Six Phlebotominae sand fly species are incriminated as biological vectors of human pathogens in Panama, but molecular corroboration is still needed. We aim at confirming the identity of Phlebotominae species documented as ...

    • Mosquito-Host Interactions during and after an Outbreak of Equine Viral Encephalitis in Eastern Panama 

      Navia-Gine, Wayra G.; Loaiza, Jose R.; Miller, Matthew J. (2013-12-10)
      Mosquito blood meals provide information about the feeding habits and host preference of potential arthropod-borne disease vectors. Although mosquito-borne diseases are ubiquitous in the Neotropics, few studies in this ...

    • Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects 

      Mitra, Joy; Guerrero, Erika N; Hegde, Pavana M; Liachko, Nicole F; Wang, Haibo; Vasquez, Velmarini; Gao, Junling; Pandey, Arvind; Taylor, J Paul; Kraemer, Brian C; Wu, Ping; Boldogh, Istvan; Garruto, Ralph M; Mitra, Sankar; Rao, KS Jagannatha; Hegde, Muralidhar L (2019-03-05)
      Genome damage and their defective repair have been etiologically linked to degenerating neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the specific mechanisms remain enigmatic. The ...

    • A multi-faceted genotoxic network of alpha-synuclein in the nucleus and mitochondria of dopaminergic neurons in Parkinson’s disease: Emerging concepts and challenges 

      Vasquez, Velmarini; Mitra, Joy; Wang, Haibo; Hegde, Pavana M; Rao, KS Jagannatha; Hegde, Muralidhar L (2020-02-01)
      α-Synuclein is a hallmark amyloidogenic protein component of the Lewy bodies (LBs) present in dopaminergic neurons affected by Parkinson’s disease (PD). Despite an enormous increase in emerging knowledge, the mechanism(s) ...

    • A Multicomponent Animal Virus Isolated from Mosquitoes 

      Ladner, Jason T.; Wiley, Michael R.; Beitzel, Brett; Auguste, Albert J.; Dupuis, Alan P.; Lindquist, Michael E.; Sibley, Samuel D.; Kota, Krishna P.; Fettere, David; Eastwood, Gillian; Kimme, David; Prieto, Karla; Guzman, Hilda; Aliota, Matthew T.; Reyes, Daniel; Brueggemann, Ernst E.; John, Lena St.; Hyeroba, David; Lauck, Michael; Friedrich, Thomas C.; O’Connor, David H.; Gestole, Marie C.; Cazares, Lisa H.; Popov, Vsevolod L.; Castro-Llanos, Fanny; Kochel, Tadeusz J.; Kenny, Tara; White, Bailey; Ward, Michael D.; Loaiza, Jose R.; Goldberg, Tony L.; Weaver, Scott C.; Kramer, Laura D.; Tesh, Robert B.; Palacios, Gustavo (2016-09-14)
      RNA viruses exhibit a variety of genome organization strategies, including multicomponent genomes in which each segment is packaged separately. Although multicomponent genomes are common among viruses infecting plants and ...

    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (American Journal of Respiratory and Critical Care Medicine, 2018-09-15)
      Tuberculosis (TB) remains the leading cause of death from a single infectious agent, followed by HIV/AIDS (1). Emerging countries, such as Panama, have not been able to curb TB infection rates. The development of novel ...

    • Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells 

      Torres-Atencio, Ivonne; Rosero, Sara; Ordoñez, Ciara; Ruiz, Michelle; Goodridge, Amador (2018-06-13)
      Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...

    • Mycobacterium bovis in Panama, 2013 

      Acosta, Fermín; Chernyaeva, Ekatherina; Mendoza, Libardo; Sambrano, Dilcia; Correa, Ricardo; Rotkevich, Mikhail; Tarté, Miroslava; Hernández, Humberto; Velazco, Bredio; de Escobar, Cecilia; H. de Waard, Jacobus; Goodridge, Amador (2015-06-01)
      Panama remains free of zoonotic tuberculosis caused by Mycobacterium bovis. However, DNA fingerprinting of 7 M. bovis isolates from a 2013 bovine tuberculosis outbreak indicated minimal homology with strains previously ...

    • Mycobacterium tuberculosis Isolates from Single Outpatient Clinic in Panama City Exhibit Wide Genetic Diversity 

      Sambrano, Dilcia; Correa, Ricardo; Almengor, Pedro; Domínguez, Amada; Vega, Silvio; Goodridge, Amador (2014-08-06)
      Understanding Mycobacterium tuberculosis biodiversity and transmission is significant for tuberculosis control. This short report aimed to determine the genetic diversity of M. tuberculosis isolates from an outpatient ...

    • New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases 

      Mitra, Joy; Guerrero, Erika N; Hegde, Pavana M; Wang, Haibo; Boldogh, Istvan; Rao, Kosagi Sharaf; Mitra, Sankar; Hegde, Muralidhar L (2014-07-17)
      The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, e.g., oxidative ...

    • New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases 

      Mitra, Joy; Guerrero, Erika N; Hegde, Pavana M; Wang, Haibo; Boldogh, Istvan; Rao, KS Jagannatha; Mitra, Sankar; Hegde, Muralidhar L (2014-07-17)
      The primary cause (s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, eg, oxidative ...

    • New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases 

      Mitra, Joy; Guerrero, Erika N.; Hegde, Pavana M.; Wang, Haibo; Boldogh, Istvan; Sharaf Rao, Kosagi; Mitra, Sankar; Hegde, Muralidhar L. (biomolecules, 2014-07-17)
      The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, e.g., oxidative ...

    • New species, phylogeny, host-associations and geographic distribution of genus Cryptosporella (Gnomoniaceae, Diaporthales) 

      Mejıa, Luis C.; Rossman, Amy Y.; Castlebury, Lisa A.; White Jr, James F. (2011-03-01)
      The phylogeny of Cryptosporella is revised to include recently discovered species. Eight species new to science are described and two new combinations are proposed, raising the total number of species accepted in Cryptosporella ...

    • Occultocarpon, a new monotypic genus of Gnomoniaceae on Alnus nepalensis from China 

      Mejía, Luis C.; Rossman, Amy Y.; Castlebury, Lisa A.; Yang, Zhu L.; White Jr, James F. (2011-06-04)
      Microfungi in the Gnomoniaceae (Diaporthales, Ascomycetes) comprise species commonly reported as pathogens and endophytes on trees and herbaceous hosts primarily from temperate forests of North America, Europe, and Japan. ...

    • Osteoblasts exhibit a more differentiated phenotype and increased bone morphogenetic protein production on titanium alloy substrates than on poly-ether-ether-ketone 

      Olivares-Navarrete, Rene; PhD, DDS; Gittens, Rolando A.; MS; Schneider, Jennifer M.; MS; Hyzy, Sharon L.; BS; Haithcock, David A.; Ullrich, Peter F. MD; Schwartz, Zvi; Boyan, Barbara D. (2012-01-12)
      Multiple biomaterials are clinically available to spine surgeons for performing interbody fusion. Poly-ether-ether-ketone (PEEK) is used frequently for lumbar spine interbody fusion, but alternative materials are also used, ...

    • Overweight, Obesity, and Older Age Favor Latent Tuberculosis Infection among Household Contacts in Low Tuberculosis-Incidence Settings within Panama 

      Cubilla-Batista, Idalina; Ruiz, Nadia; Sambrano, Dilcia; Castillo, Juan; de Quinzada, Markela O; Gasteluiturri, Begoña; Goodridge, Amador (2019-05-01)
      Latent tuberculosis infection (LTBI) remains the main source of new active tuberculosis (TB) cases worldwide. Household close contacts (HCCs) are at high risk of acquiring LTBI and subsequent development of TB. In this ...