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Storage in ultra-low-temperature decreases the levels of IgM anticardiolipin antibody in serum samples from tuberculosis patients
(2014-06-01)
The evaluation of novel tuberculosis (TB) biomarkers relies on analysis of previously stored sample sets. We aimed to determine the effect of storage temperature on serum IgM anticardiolipin antibody levels in samples from ...
Antitrypanosomal Alkaloids from the Marine Bacterium Bacillus pumilus
(2012-09-18)
Fractionation of the ethyl acetate extract of the marine bacterium Bacillus pumilus isolated from the black coral Antipathes sp. led to the isolation of five compounds: cyclo-(L-Leu-L-Pro) (1), 3-hydroxyacetylindole (2), ...
Anti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oil
(2014-01-13)
Background Plinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil of this plant has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS of this ...
Detecting space-time clusters of dengue fever in Panama after adjusting for vector surveillance data
(2019-09-23)
Long term surveillance of vectors and arboviruses is an integral aspect of disease prevention and control systems in countries affected by increasing risk. Yet, little effort has been made to adjust space-time risk estimation ...
Agua Salud alphavirus defines a novel lineage of insect- specific alphaviruses discovered in the New World
(2020-01-01)
The genus Alphavirus harbours mostly insect- transmitted viruses that cause severe disease in humans, livestock and wildlife. Thus far, only three alphaviruses with a host range restricted to insects have been found in ...
Asociación entre cognición y depresión en adultos mayores panameños con cognición normal y deterioro cognitivo leve
(2020-07-29)
La depresión y el deterioro cognitivo leve (DCL)en el adulto mayorestánrelacionadoscon el desarrollo de distintos tipos de demencia y disminución en la funcionalidad. Se realizó un estudio descriptivo de corte transversal ...
Revisiting metal toxicity in neurodegenerative diseases and stroke: Therapeutic potential.
(2015-01-23)
Excessive accumulation of pro-oxidant metals, observed in affected brain regions, has consistently been implicated as a ontributor to the brain pathology including neurodegenerative diseases and acute injuries such as ...
COVID-19 pandemic in Panama: lessons of the unique risks and research opportunities for Latin America
(2020-06)
The Republic of Panama has the second most unequally distributed wealth in Central America, has recently entered the list of countries affected by the COVID-19 pandemic, and has one of the largest testing rate per inhabitant ...
Intestinal volvulus in the pump twin of a twin reversed arterial perfusion (TRAP) sequence after laser therapy at 18 weeks: a case report
(2020-08-08)
Background: Twin reversed arterial perfusion sequence is a rare and potentially lethal condition affecting approximately 1% of monochorionic twin pregnancies and 1 in 35,000 pregnancies overall. An apparently normal (pump) ...
Mycobacterial Lipids Induce Calcium Mobilization and Degranulation of Mast Cells
(2018-06-13)
Cells and culture conditions. Murine MCs from line C1.MC/C57.1 (C57 MC) were kindly provided by Dr. Stephen Galli (Stanford University) and cultured in Dulbecco’s modified Eagle’s medium according to standard methods (9). ...