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Vacuolar Targeting of Cry1Ac and its Effects on Expression and Stability in Tobacco.
(2014-07-01)
Increasing heterologous expression of delta endotoxins of Bacillus thuringiensis in transgenic plants is being actively pursued as a
means to increase their efficacy and to delay insect resistance. To examine if vacuoles ...
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group
(2018-01-12)
We reported previously the discovery of the potent antimalarial 40-membered macrolide bastimolide A (1) from the tropical marine cyanobacterium Okeania hirsute. Continued investigation has led to the discovery of a new ...
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015
(2016-10-08)
In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 ...
Malarial hemozoin: From target to tool
(2014-02-17)
Malaria is an extremely devastating disease that continues to affect millions of people each year. A distinctive attribute of malaria infected red blood cells is the presence of malarial pigment or so-called hemozoin. ...
A review on the wettability of dental implant surfaces I: Theoretical and experimental aspects
(2014-02-28)
The surface wettability of biomaterials determines the biological cascade of events at the biomaterial/ host interface. Wettability is modulated by surface characteristics, such as surface chemistry and surface topography. ...
L-Asparaginase a Biotherapeutic for Acute Lymphoblastic Leukemia-A Molecular Perspective
(2017-10-01)
L-asparaginase (L-asparagine amino hydrolase) is an enzyme which was clinically proved as an antitumor agent to treat acute lymphoblastic leukemia. It catalyzes L-asparagine hydrolysis to L-aspartate and ammonia, and the ...
Development of Monoclonal Antibodies Against Cry1Ac/Ab Protein for Designing of Sandwich ELISA to Detect BT Toxin from Cotton Seeds and Leaves
(2019-12-30)
The design of the study is to develop monoclonal antibodies against Cry1Ac/Ab protein for designing os sandwich ELISA(hybridoma technology). Hybridoma technology was invented by Cesar Milstein and Georges J.F Kohler in the ...
Automated Synchronization of P. falciparum using a Temperature Cycling Incubator
(2011-04)
As malaria keeps affecting millions of lives every year, research based in culture of Plasmodium falciparum in vitro needs to be efficient and accurate. The development of better techniques and methodologies for the growth ...
Effect of Post Weld Heat Treatments on the Elevated Temperature Mechanical Properties of Ti6Al4V Friction Welds
(2018-02-09)
The {\alpha}+\b {eta} titanium alloy (Ti6Al4V) has been successfully joined using rotary friction welding. To investigate the influence of post weld heat treatments on the microstructure and mechanical properties of the ...
Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
(2018-11-10)
Background Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of ...