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Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum
(2018-08-29)
Chemical examination of the octocoral-associated Bacillus species (sp.) DT001 led to the isolation of pumilacidins A (1) and C (2). We investigated the effect of these compounds on the viability of Plasmodium falciparum ...
A review on the wettability of dental implant surfaces II: Biological and clinical aspects
(2014-04-05)
Dental and orthopedic implants have been under continuous advancement to improve their interactions with bone and ensure a successful outcome for patients. Surface characteristics such as surface topography and surface ...
Osteoblasts exhibit a more differentiated phenotype and increased bone morphogenetic protein production on titanium alloy substrates than on poly-ether-ether-ketone
(2012-01-12)
Multiple biomaterials are clinically available to spine surgeons for performing interbody fusion. Poly-ether-ether-ketone (PEEK) is used frequently for lumbar spine interbody fusion, but alternative materials are also used, ...
In vitro and in vivo experimental models for drug screening and development for Chagas disease
(2010-03-02)
Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of Latin America. Although the occurrence of acute cases sharply has declined due to Southern Cone Initiative efforts to control ...
Mycobacterium bovis in Panama, 2013
(2015-06-01)
Panama remains free of zoonotic tuberculosis caused by Mycobacterium bovis. However, DNA fingerprinting of 7 M. bovis isolates from a 2013 bovine tuberculosis outbreak indicated minimal homology with strains previously ...
HS-C reactive protein and red blood cell distribution width as effective markers for hypertension
(International Journal of Advances in Medicine, 2016-04-06)
Background: Hypertension or elevated blood pressure is one of the leading causes of morbidity and mortality. HsCRP, which is a known marker for CVD, is also one of the predictive markers of inflammation processes which ...
Separation of Plasmodium falciparum Late Stage-infected Erythrocytes by Magnetic Means
(2013-02-20)
Unlike other Plasmodium species, P. falciparum can be cultured in the lab, which facilitates its study 1. While the parasitemia achieved can reach the ≈40% limit, the investigator usually keeps the percentage at around ...
Deterioro cognitivo leve y enfermedad de Alzheimer: Revisión de conceptos
(Investigación y Pensamiento Crítico, 2016-05-01)
La enfermedad de Alzheimer (EA) es una enfermedad neurológica degenerativa que afecta a más de 46 millones de personas alrededor del mundo. Representa el tipo de demencia más común en los adultos mayores y cursa con una ...
New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases
(2014-07-17)
The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown. However, the association of certain etiological factors, e.g., oxidative ...
A Multicomponent Animal Virus Isolated from Mosquitoes
(2016-09-14)
RNA viruses exhibit a variety of genome organization strategies, including multicomponent genomes in which each segment is packaged separately. Although multicomponent genomes are common among viruses infecting plants and ...