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Are pulmonary fibrosis and Alzheimer's disease linked? Shared dysregulation of two miRNA species and downstream pathways accompany both disorders
(2017-12-08)
As neuroscientists, we were intrigued when Huang et al. (1) reported that miR101 can attenuate pulmonary fibrosis (PF)2 through suppression of Wnt family member 5A (WNT5A). Accumulating evidence suggests that prima facie ...
Ascertaining fetal Zika virus infection based on IgM antibody test in endemic settings
(2017-06-01)
First, the authors' rationale to include a Zika virus (ZIKV)‐specific IgM antibody test as part of the positive case definition, despite the test's cross‐reactivity with other Flavivirus infections and immunizations, is ...
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
(2018-11-10)
Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver ...
A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
(2014-10-11)
The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the early paradigm of cell replacement and differentiation as a therapeutic mechanism of action, evidence is mounting that the ...
Imaging mass spectrometry and MS/MS molecular networking reveals chemical interactions among cuticular bacteria and pathogenic fungi associated with fungus-growing ants
(2017-07-17)
The fungus-growing ant-microbe symbiosis is an ideal system to study chemistry-based microbial interactions due to the wealth of microbial interactions described, and the lack of information on the molecules involved ...
Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants
(2014-04-08)
The use of spinal implants for spine fusion has been steadily increasing to avoid the risks of complications and donor site morbidity involved when using autologous bone. A variety of fusion cages are clinically available, ...
Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo
(2018-05-22)
Leptospira borgpetersenii serovar Hardjo colonizes cattle kidneys and may occasionally infect humans and other mammals. Strains belonging to two clonal subtypes (types A and B) with marked differences in their pathogenicity ...
High infestation of invasive Aedes mosquitoes in used tires along the local transport network of Panama
(2019-05-27)
Background: The long‑distance dispersal of the invasive disease vectors Aedes aegypti and Aedes albopictus has intro‑ duced arthropod‑borne viruses into new geographical regions, causing a significant medical and economic ...
Thermo-Energetic Study in Blood Infected with Plasmodium falciparum radiated at 2.45GHz
(IEEE, 2019-11-25)
Malaria is a disease that affects the world, caused by the parasite Plasmodium which resistance is emerging to medications that usually control it. Therefore, it is essential to seek alternative treatments like this one, ...
Evaluation of antiparasitic, anticancer, antimicrobial and hypoglycemic properties of organic extracts from Panamanian mangrove plants
(2018-01-02)
To investigate 33 organic extracts of mangrove plants for: antiparasitic, anticancer, and antibacterial activities, as well as their ability to inhibit the activity of the 毩-glucosidase enzyme. Methods: Leaves from all ...